Get 4X Points†† on ALL Makeup! Ends 3/4. ††Exclusions/terms apply. Use code MAKEUPMATH ▸

Sign Infor FREE Shipping

Long-Lasting Serums

Sephora customers often prefer the following products when searching for Long-Lasting Serums.

If you're looking for a way to add moisture and nutrients to your skin, serums are a great option. They're easy to use, and they can last for months before you need to replace them. Here are some of the best long-lasting serums on the market today.

Danessa Myricks BeautyYummy Skin Glow Serum with Hyaluronic Acid & Niacinamide

Size: 1.1 oz/ 32.5mL·ITEM: 2575330

Color: Juice Boost - Warm Copper/Bronze for all skin types & tones

405 Reviews

$48.50

Buy Now

Beautiful glow and long wear foundation...I noticed a true glow shining through my foundation when I applied this serum as the last step in my skincare routine. I would describe my skin as feeling bouncy, hydrated and youthful when using this serum....In- fact you Need this for youthful beautiful skin and beautiful long lasting makeup!

What it is: A skincare-infused, radiant priming serum that hydrates, preps, and protects skin for a lit-from-within glow.

Finish:
Radiant

Skin Type:
Normal, Oily, Dry, Combination

Concerns: Dryness, Pores, and Uneven Skin Tone

Highlighted Ingredients:
- Vitamin C: Visibly brightens dullness and protects skin from free radicals.
- Niacinamide: Minimizes the appearance of pores.
- Hyaluronic Acid: Hydrates and visibly plumps fine lines and wrinkles.

Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, sulfates SLS & SLES, triclocarban, triclosan, and contains less than one perc

$125.00

This has truly quenched my dry dull skins thirst. The best part is that the hydration is long lasting.. ...It is great for long lasting hydration in skin.

What it is: A lightweight serum powered by AquaPort Technology that delivers dual-weight hyaluronic acid faster and deeper into skin for instant, long-lasting hydration.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Dryness, Dullness, Loss of Firmness and Elasticity

Formulation: Serum

Highlighted Ingredients:
- AquaPort Technology: Transports hydration faster and deeper into the skin​.
- Rosemary Peptide Complex: Fights skin fatigue and accelerates natural recovery to help skin bounce back.
- Blue Light-Activated Algae Extract: Combats digital aging by improving the appearance of dark spots, fine lines, and wrinkles.

Ingredient Callouts: Free of parabens, formaldehyde

$106.00

Long lasting hydration...This long lasting hyaluronic acid serum deeply hydrates my skin, prevents dryness and makes skin brighter and plump. ...Long-lasting hydration...The serum plumping up the skin and long-lasting hydrating it with hyaluronic acid.

What it is: A hyaluronic acid serum that hydrates and helps prevent future dehydration.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Dryness, and Loss of Firmness and Elasticity

Formulation: Lightweight Serum

Highlighted Ingredients:
- Hyaluronic Acid: Helps penetrate skin's surface for intense hydration.
- Algae Extract-Infused Moisturizing Matrix: Binds water to the skin for both immediate and long-lasting hydration.
- Polyglutamic Acid from Fermented Soybean: Supports skin's hydration reserves from within.

Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate.

$95.00

This is one of the best serums I've ever used. I got so many compliments on my skin when I was using this. ...Great serum. Light and long lasting. I am a big fan of l’occitane.

What it is: A radiance-boosting serum that hits reset on dull-, tired-looking skin with an infusion of immortelle essential oil.


Skin Type: Normal, Dry, Combination, and Oily


Skincare Concerns: Dullness


Highlighted Ingredients:
- 100% Organic Immortelle Essential Oil: Packed with powerful antioxidants to fight visible signs of aging.

- Immortelle Sap-Like Extract: Soothes skin and supports recovery from daily stress.

- Acmella oleracea Extract: Rapidly smooths skin.


Ingredient Callouts: Free of parabens and sulfates SLS & SLES.

Bobbi BrownExtra Plump Hydrating Lip Oil

Size: 0.2 oz·ITEM: 2769107

Color: Bare Rose - milky nude pink

769 Reviews

$50.00

And I noticed how my lips were still hydrated after 3-4 hours which is very long lasting for a lip serum if you ask me....This luxurious Lip Serum provides deep long lasting hydration, smoothness, and a subtle plumping effect.

What it is: A plumping lip oil that deeply replenishes lips as it delivers a fuller look and lasting shine, the look of a lip gloss with lip-nourishing benefits.


Highlighted Ingredients

-Hyaluronic Acid: hydrates and smooths

-Blend of Botanical Oils: conditions, nourishes and soothes


Formulation Type: 
Lip Oil, Lip Gloss, Lip Balm and Treatment, Lip Plumper


Benefits: Hydrating, Long-wearing, Plumping

$154.00

It uses ultra-stable Vitamin C and nourishing Pro-Vitamin D Complex to repair my skin’s moisture barrier and provide long-lasting brightness and rapid, intense hydration. ...These powerful ingredients work together to repair the skin’s moisture barrier, delivering long-lasting brightness and immediate hydration.

What it is: A vitamin C and pro-vitamin D overnight serum that restores the moisture barrier for long-lasting radiance and hydration.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Dryness, Dullness, and Uneven Texture

Formulation: Serum

Highlighted Ingredients:
- Ultra-Stable Vitamin C: Provides lasting brightness.
- Pro-Vitamin D Complex: Hydrates and nourishes moisture barrier.
- 10% Glycerin and Jojoba Ester: Support visibly plump, hydrated skin.

Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, sulfates SLS & SLES, triclocarban, triclosan, and c

$43.50

When I first started using this it was pretty humid where I live but it smoothed my hair so well I was almost entirely frizz-free even on day 3 hair. Those results didn’t last long though and I am now back to a layer of frizz whether I use this product or not even though humidity has reduced. ...I really love this serum! Just like the shampoo and conditioner, you can feel how great the quality is compared to other serums and brands.

What it is: A finishing serum that creates silky smoothness, lasting frizz control, and provides heat protection for normal to thick, frizzy hair.

Hair Type: Straight, Wavy, Curly, and Coily

Hair Texture: Medium and Thick

Hair Concerns:
- Frizz
- Heat Protection
- Color Protection

Key Benefits:
- Smoothing and frizz control
- Heat protection
- Extraordinary color protection

Highlighted Ingredients:
- Camellia: Smooths and nourishes hair.
- Shea Butter: Softens hair.
- Xylose: Protects hair from heat styling and damage.

$64.99

It’s so hard to find a styling product that doesn’t leave my hair feeling crispy or is actually long-lasting..until now! I have always been a fan of Dyson (their hair tools are my favorite!) ...I love the lightweight formula and the long-lasting hold. It works amazing defending my hair against humidity.

What it is: A lightweight post-styling serum that provides flexible, all-day hold for smooth, shiny, frizz-free hair. For use on dry and styled hair to hold and define style.


Hair Texture: Straight, Wavy, Curly, and Coily


Hair Type: Fine, Medium, and Thick


Hair Concerns:

- Hold & Style Extending

- Shine


$236.00

Cleanse, tone, serums, moisturizer, primer, makeup then spf. Hope this helps!...Amazing serum, especially for anti aging. I've been using it regularly for the last 5 years and wouldn't go back to anything else.

Which skin type is it good for?
✔ Normal
✔ Combination
✔ Dry

What it is:
A powerful serum that detoxifies, regenerates, and boosts skin for a revitalized complexion.

Solutions for:
- Dullness and uneven texture

If you want to know more…
Daily, skin faces an onslaught of aggressors including UV rays, stress, and pollution. The solution: the new One Essential, with a more powerful formula that targets 100 percent of both outdoor (microparticles, heavy metals) and—for the first time—indoor toxins (per an in vitro test on ingredients) such as carpet, glue, varnishes, and electronic devices.

$40.50

I am so excited that I got to try this green tea hyaluronic acid serum. It contains Green Tea and encapsulated hyaluronic acid which gives a long lasting hydration and glow to my skin, can be used daily....Green Tea Hyaluronic Acid Refillable Serum This daily, skin-quenching serum infused with Green Tea and encapsulated hyaluronic acid gives me long lasting hydration and glow. ...Great serum

What it is: A daily, skin-quenching serum infused with Green Tea and encapsulated hyaluronic acid for lasting hydration and glow.    


Skin Type: Normal, Dry, Combination, and Oily


Skincare Concerns: Dryness and Uneven Texture


Formulation: Lightweight Serum


Highlighted Ingredients:

-Green Tea Water + Encapsulated Hyaluronic Acid: has higher hydration power than Hyaluronic Acid alone 

-Panthenol: hydrates and helps fortify skin's moisture barrier

Products related to Long-Lasting Serums

Lightweight Serums
“I *love* this serum! It's lightweight and absorbs into your skin super quickly, so it feels effective (as compared to other serums, which leave a sticky feeling or layer on your face”
Eye Serums
“Easily the coolest (literally and figuratively) eye serums/packaging I’ve ever tried. I love the eye roller to help further depuff my eyes”
Water-Based Serums
“It feels nice on the skin though, it is quite a heavy serum, much different from typical hyaluronic serums”
Age Defying Serums
“These aromas represent our high quality ingredients working together to deliver noticeable results. This comprehensive age-defying treatment has 29 high performance ingredients to provide unparalleled results”
Gel Serums
“This replaced Skinceuticals B5 gel for me, it’s that good. Most hyaluronic acid serums pill under certain creams, but this serum works with all other products I’ve used”
Top Facial Serums
“I have used other serums in the past from many different brands, but I can honestly say for this price the brand and the product it’s really good it really smooth out your skin”
Primer Serums
“This is a great primer serum for my oily skin. I always like to use hydrating products under my makeup and target oily areas with other primers and this works amazing for both”
Serum For Fine Lines
“Just started using this so cannot say if it helps with fine lines but definitely leaves the skin very smooth, plumped and well hydrated afterwards”
Sunscreen Serums
“This tinted serum tends to pill up in combination with my mattifying spf but seems to work fine with my more dewy ones although this combination can feel a bit too dewy at times”
Repair Serums
“Wow, this Clinique Smart Clinical Repair Wrinkle Correcting Serum is a game changer”

Related Content:

Curling Wands & Curling Irons, Best Highlighter Luminizer, Best Hair Products For Dry Hair, Best Eyebrow Makeup in 2026, Best Eye Creams of 2024, Best Foundations for Oily Skin in 2024, Best Brow Products For You | Brow Quiz, Best Affordable Makeup in 2026, Best Colognes for Men in 2024