Choose a FREE trial-size moisturizer* with $30 spend. *Terms apply. Use code MOISTURIZE

Sign Infor FREE Shipping

Skin Barrier Repair Serums

Sephora customers often prefer the following products when searching for Skin Barrier Repair Serums.

Achieve a healthy, radiant complexion with this collection of skin barrier repair serums. Designed to nourish and strengthen your skin's protective barrier, these serums work tirelessly to restore moisture, soothe irritation, and promote a smoother, more even-toned complexion. Whether you're battling dryness, sensitivity, or environmental stressors, this range of skin barrier repair serums is here to support your skin's natural defenses and leave you with a glowing, revitalized visage.

Dr. Barbara SturmNight Serum — Night Serum for Skin Renewal, Hydration & Barrier Support

ITEM: 2330355

Size: 1/30

53 Reviews

$445.00

Buy Now

This serum truly works wonders. I apply it every night to repair my skin while I sleep and I've noticed a big improvement with dryness and irritation. ...On retinal night, I apply the night serum before my retinal to provide a protective skin barrier.

What it is: A hyaluronic acid serum that boosts skin’s nightly regeneration phase to help repair its barrier function and reduce the appearance of wrinkles.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Pores, Dryness, and Loss of Firmness and Elasticity

Formulation: Lightweight Serum

Highlighted Ingredients:
- Extracts from Poria Cocos and Beta-Glucan: Help support skin barrier function.
- Plankton Extract: Helps reduce the appearance of fine lines and wrinkles.
- Senna Alata Extract: Supports the skin’s natural reparative process.

Ingredient Callouts: Free of sulfates SLS and SLES, parabens, formaldehydes, formaldehyde-releasing agents, phthalates.

$303.00

This smooths the skin barrier leaving behind velvety soft skin and a beautiful lit from within glow!...As with all of the La Mer products that contain their miracle broth I think it is a great serum that helps the skin barrier. It is also so good for the redness and the skin feels soft and smooth.

What it is: A mini-size velvety serum to help rebuild and protect your skin’s natural barrier with the concentrated Miracle Broth™ to help visibly calm redness and inflammation.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines/Wrinkles, Dryness, and Redness

Formulation: Liquid

Highlighted Ingredients:
- Stabilizing Ferment: Marine-sourced ferment visibly strengthens irritated skin.
- Concentrated Miracle Broth™: La Mer's super-concentrated form of cell-renewing Miracle Broth™ helps calm the look of redness and other signs of inflammation.
- Lime Tea Concentrate: Antioxidants protect skin from inflammation from environmental stressors.

$575.00

The concentrate from Lamer is a very velvety-textured serum that focuses on strengthening the skin barrier protecting it from inflammation. ...LA MER THE CONCENTRATE is a barrier building antioxidant powerhouse serum. The serum feels velvety and luxurious.

What it is: A potent barrier serum to strengthen, stabilize, and soothe skin against daily irritants.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Dryness, and Dullness

Formulation: Serum

Highlighted Ingredients:
- Concentrated Miracle Broth™: Powerhouse elixir calms the look of redness while energizing renewal.
- Lime Tea Concentrate: Proprietary antioxidant, neutralizes free radicals to protect skin.
- The Stabilizing Ferment: Proprietary ferment supports fragile, irritated skin.

Ingredient Callouts: Free of parabens, phthalates, and sulfates SLS & SLES.

What Else You Need to Know: Antioxidant-rich serum defends skin ag

$145.00

I did not find this product (or the cream for that matter) anymore effective than using a Cerave cream for skin barrier repair. This serum absorbs quickly, has a slight scent but that must be from the ingredients- not a pleasant fragrance. ...Ceramide serum for barrier repair. Lightweight and non-greasy.

What it is: A lightweight, fast-absorbing serum formulated to support sensitized skin and its protective barrier.

Skin Type: Normal and Dry

Skincare Concerns: Redness and Dryness

Formulation: Lightweight Serum

Highlighted Ingredients:
- Peptide Complex and Ceramides: Relieve redness and irritation while working to support skin’s protective barrier.
- Cucumber Seed Oil: Calms and soothes.
- Tasmannia Lanceolata Fruit Extract: Works to calm skin.

$77.00

Amazing for Skin Barrier Repair...This serum is really good for repairing the skin barrier ! ...Perfect barrier repair serum...For that reason it’s great day or night. This is the perfect barrier repair serum. Also love the packaging!

What it is: A high-potency serum with 10 potent, active ingredients such as niacinamide and peptides clinically shown to visibly plump, firm, and reduce fine lines.


Skin Type: Normal, Dry, Combination, and Oily


Skincare Concerns: Fine Lines and Wrinkles, Loss of Firmness and Elasticity, and Dryness

$68.00

Great barrier repair product...This is a really great soothing and moisturizing serum. I’m currently using tretinoin and my skin is sensitized and peeling a bit and this has been a great addition to my routine to soothe and help repair my skin barrier while my skin adjusts. ...Barrier Repair in a Bottle...Loved this product so much. helped repair my skin barrier when it was severely damaged from over exfoliating.

What it is: A creamy, supercharged serum that visibly restores the skin barrier to calm sensitivity, intensely hydrate, and support the skin microbiome.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Dryness, and Dullness

Formulation: Lightweight Serum

Highlighted Ingredients:
- Hydrating Triple-Lipid Complex: Skin-similar blend that restores ceramide and fatty acid levels.
- Visibly Plumping Seaweed Hyaluronate Blend: Small particles that intensely hydrate for dewy, glass-like skin.
- Peony Root Complex: Supports the skin barrier and visibly enhances radiance.

Ingredient Callouts: This product is vegan, gluten-free, and cruelty-free.

$55.50

Barrier Blessing...I have been trying to repair my skin barrier and this stuff has been a blessing let me tell you. ...Helping me repair my barrier!...I mostly use this as a moisturizer as I have ruined my skin barrier exfoliating. This is gentle, not fragranced, compact product.

What it is: This 98% natural balm-to-serum, intensely hydrates, repairs and soothes with our Moisture Repair Complex - a blend of 16 nourishing ingredients.

Skin Type: Normal, Dry, and Combination

Highlighted Ingredients:
- Hyaluronic Acid: Boosts and replenishes skin's hydration levels.
- Blue Tansy Flower Extract: Soothes skin and protects against free radicals and environmental stressors.
- Centella asiatica: Cares for and calms irritated skin.

$73.00

It does offer some moisture and skin barrier repair but I wasn’t impressed with how it did with the redness claims....Overall, a reliable choice for addressing redness and supporting skin barrier repair.

What it is: A potent face serum with soothing cica complex and allantoin to quickly soothe the skin barrier and reduce redness for healthier-looking skin.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Dryness and Redness

Highlighted Ingredients:
- Cica Complex (Centella Asiatica): Deeply soothes skin.
- Allantoin: Supports skin’s barrier.

Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, sulfates SLS & SLES, triclocarban, triclosan, and contains less than one percent synthetic fragrance. It is also gluten-free.

What Else You Need to Know: This fragrance-free, lightweight face serum was formulated with sensi

$80.00

Great dual chamber product for redness prone skin...It did not completely erase the redness but worked well with makeup for the coverup. I also love the barrier repair cream, especially after a day of retinol, it prevented peeling....I loved the color correcting side as it instantly covered up my redness, and didn’t leave behind any stickiness. The barrier repair serum is a lightweight treatment that helps heal redness over time, and repair the barrier.

What it is: A serum that targets redness and blotchiness immediately and over time.

Skin Type: Dry, Combination, and Oily

Skincare Concerns: Redness and Uneven Texture

Formulation: Lightweight Serum

Highlighted Ingredients:
- Hexapeptide-9 and Biomimetic Peptides: Patented peptide shown to nourish skin barrier and reduce redness.
- 5% Azelaic Acid and Annonasense: Calms effects of stress on skin for visibly less red, bumpy skin.
- Snow Mushroom and Centella Stem Cells: Provide a boost of hydration and support skin barrier.

Ingredient Callouts: This product is vegan, gluten-free, cruelty-free, and comes in recyclable packaging.

What Else You Need to Know: This is the first hi

$70.00

Helped my sensitive skin barrier...I’ve been using this for about two weeks now and it definitely helped with sensitivity, I can’t speak to the redness because I don’t suffer from it. But it helped repair my skin barrier and left my skin feeling smooth! ...Godsend for the winter months dry skin...Over a few weeks of use, I noticed visible improvements in my skin barrier repair and an alleviation of dryness.

What it is: A moisturizer for sensitive skin with soothing Centella Asiatica. This face cream instantly reduces visible redness and helps repair damage to the skin barrier. Derm tested.


Skin Type: Normal, Dry, and Combination


Skincare Concerns: Dryness and Redness

Products related to Skin Barrier Repair Serums

Skin Barrier Repair Cream
“This moisturizer has saved my skin multiple times. With age, my skin started becoming a lot more sensitive and I was constantly destroying my skin barrier, after a week of covering my face with this, it completely soothed my acne and red marks”
Barrier Repair Moisturizers For Oily Skin
“I am really impressed with this moisturizer. I’ve been using consistently for about 3 weeks and notice an improvement in my skin barrier”
Repair Serums
“It’s dermatologist tested so it’s pretty trustworthy. It repairs the skin and keeps it hydrated. The whole package looks high quality”
Serums With Ceramides
“Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide. Thicker than other serums”
Skin Repair Creams
“It hydrates the skin for a long time. Cream that fights wrinkles helps to feed and fortify the skin for smoother, younger-looking skin”
Moisture Barrier Creams
“Now my AM routine is: wash, tone, essence, copper peptide, Prejuvenation serum and cream. I’ve used many, many, many face creams and thought they were irritating, did nothing or were good enough”
Serums For Dry Skin
“It smells great, a very clean green scent. On my dry skin it absorbs in under a minute so I don’t have to wait a long time to apply moisturizer”
Moisturizing Serums
“I absolutely love this lip serum and cannot live without it. I have been using this since 2016 and a TINY dot goes a long way”
Water-Based Serums
“I received this product as a sample from topbox and I was absolutely amazed by the product packaging. The serum is water based and very light on skin and texture is very smooth”
Sunscreen Serums
“The Sturm glow is real! I can wear this serum her glow drops and spf and leave the house without feeling insecure”

Related Content:

Face Serum & Face Treatments, Best Hair Products For Dry Hair, Best Products for Dry Hair in 2026, Best Eye Creams of 2024, Best Foundations for Oily Skin in 2024, Best Face Moisturizers, Best Brow Products For You | Brow Quiz, Eyebrow Serums, Night Serums