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Sephora customers often prefer the following products when searching for Supplements Over $40.

Browse the top-ranked list of Supplements Over $40 below along with associated reviews and opinions.

ITEM 2356756
exclusive· limited edition· buzzworthy· online only
$40.00

It is so worth it...Love love love it...I went through one bottle of this product and I would buy again, but I'm not rushing to pay the $40 price tag... worked well- I felt better from the inside out, but I don't know that it dramatically or miraculously cured any breakouts for me...My skin has gotten increasingly better before I began taking these pills so it's hard for me to know if it helps with acne, however it definitely adds a glow to my skin that I didn't have before
Beauty Benefit: Acne/Clearer Skin, Hydration, and Gut Support

What it is: A specialized pre+probiotic blend that balances the gut, reduces non-cystic acne, and improves dry skin (previously named Skin Heroes).

What it tastes like: No flavor

How to use: Take two capsules per day, with or without food

When to expect results: Four weeks

Highlighted Ingredients: - Prebiotic Konjac Root: Helps feed the good bacteria in your gut to improve balance.
- Nine Strains, 40 Billion Organisms (at time of manufacture): Help support the immune system, protect the skin-gut axis, and improve skin barrier function.
- Soil-based and Live Strain Probiotics

What Else You Need to Know: Contains nine ultra-targeted strains of good bacteria that impact the gut-skin axis to reduce acne and dryness. Konjac root, a prebiotic, ensure these strains grow and flourish in the gut. While not necessary, HUM Nutrition recommends refrigerating after opening to maintain maximum potency.

Clinical Results: Based on a dermatologist-supervised study of women with non-cystic acne taking Skin Heroes for 60 days:
- 88% reported a decrease in breakouts
- 81% reported an improvement in digestion

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
ITEM 1735786
exclusive· limited edition· buzzworthy· online only
$40.00

Beauty Benefit: Hair, Skin, and Nails and Hydration

What it is: A collagen supplement with hyaluronic acid to support skin elasticity and firmness.

What it tastes like: No flavor

How to use: Take three capsules per day with food

Dosage: Three capsules per day

When to expect results: Four to six weeks

What Else You Need to Know: Collagen Love features a unique skin protection blend of vitamin C, hyaluronic acid, and types I and III collagen. Together, these clinically proven nutrients protect skin while minimizing the appearance of fine lines and promoting skin elasticity.*

Clinical Results: In a double-blind, placebo-controlled trial, 69 women aged 35-55 years were randomized to receive 2.5 g or 5.0 g of collagen or placebo once daily for 8 weeks. At the end of the study, skin elasticity in both collagen dosage groups showed a statistically significant improvement in comparison to placebo.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Research results: In a double-blind, placebo-controlled trial, 69 women aged 35-55 years were randomized to receive 2.5 g or 5.0 g of collagen or placebo once daily for 8 weeks. At the end of the study, skin elasticity in both collagen dosage groups showed a statistically significant improvement in comparison to placebo. In a randomized, double-blind, placebo-controlled clinical study it was found that ingested hyaluronic acid increased skin moisture and improved treatment outcomes for patients with dry skin.
ITEM 1650183
exclusive· limited edition· buzzworthy· online only
$40.00

Beauty Benefit: Anti-Aging

What it is: A vegetarian supplement with vitamin C to help protect and rejuvenate your skin.*

What it tastes like: No flavor

How to use: Take two capsules in the morning with food

Dosage: Two capsules per day

When to expect results: Four to six weeks

What Else You Need to Know: Defy signs of aging with Turn Back Time. Its unique formula helps keep UV damage under control and protect your skin from stress and pollution with a combination of clinically researched, age-defying plant extracts. It’s the perfect complement to any anti-aging routine to slow signs of wrinkles.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
ITEM 2247690
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$40.00

Beauty Benefit: Skin Cell Turnover, Skin Hydration and Texture, and Promotes Optimal Sleep

What it is: An overnight skin cell renewal supplement with ceramides, CoQ10, ferulic acid, valerian root, and passion flower that works while you sleep.

How to use: Take two soft gels at bedtime, with or without food

Dosage: Two soft gels

When to expect results: Four to six weeks

What Else You Need to Know: Your skin repairs and renews while you sleep. Mighty Night boosts overnight renewal by supporting skin and body cell turnover, scavenging free radicals, promoting optimal sleep, and improving signs of aging—resulting in a fresh complexion. A hint of peppermint oil complements your bedtime routine.

Clinical Results: In a placebo-controlled clinical study on 60 volunteers presenting dry and wrinkled skin, results showed:
- Significant reduction in the look of wrinkles, microrelief lines, and improved skin smoothness
- Reduced some visible signs of aging
- Valerian root, passion flower, and hops showed significant improvements in total sleep time, sleep latency, number of nightly awakenings, and insomnia severity index scores

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
ITEM 1160084
exclusive· limited edition· buzzworthy· online only
$42.00

I am so so impressed...Within a week of taking these, (twice a day) my skin was brighter, less dull, and my undereye circles are gone
What it is:
A supplement that helps to regulate weight and perfect skin.

What it is formulated to do:
Perricone MD Omega 3 Dietary Supplement is designed to elevate mood, regulate weight, and support cardiovascular health. It provides a multitude of benefits for the skin and the whole body.

What else you need to know:
This superstar of supplements is derived from wild sockeye salmon—the purest and most powerful resource of omega 3 and DMAE.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Size 6.7 oz/ 200 mL · ITEM 2260198
exclusive· limited edition· buzzworthy· online only
$45.00

Beauty Benefit: Energy and Focus, and Skin, Hair, and Nails

What it is: A liquid multi-vitamin with a high absorption rate that improves hair, skin, and nails with vitamin C, vitamin E, and biotin.

What it tastes like: Natural Berry Flavor

How to use: One teaspoon a day, with or without food.

Dosage: One Teaspoon per Day.

When to expect results: One Month

What Else You Need to Know: DLMD contains 13 essential vitamins, five minerals, and one bio flavonoid complex—ll that your body needs. This special formula has extremely high absorption rates (98% compared to 20% for pills and gummies) and is fast acting. It was developed by a medical doctor.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
ITEM 2298891
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$45.00

Beauty Benefit: Immunity Support, Gut Support, and Energy and Focus

What it is: A super-yummy gummy supplement to make it easy to eat your greens every day, as 87 percent of Americans don’t get their daily minimum requirement of greens.

What it tastes like: Slightly tangy, mildly herbal, barely sweet, and truly delicious

How to use: Take two gummies per day, ages four and up, and chew thoroughly before swallowing

Dosage: Two per day

When to expect results: Within a week

What Else You Need to Know: In 2015, founder Dawn Russell introduced 8Greens, the world’s first effervescent tablet that contains eight real greens. Over 40 million have been sold, but Dawn’s mission to find new ways to make getting these greens fit anyone’s life continues. The 8Greens Gummy: another great way to get your greens.

Free from niacin, dairy, gluten, and saturated or trans fats. This product is cruelty-free. Two gummies contain as much vitamin B6 as six cups of spinach, vitamin C as six oranges, zinc as three cups of peas, vitamin B12 as seven cups of milk, and vitamin B5 (pantothenic acid) as 15 cups of broccoli.
ITEM 654293
exclusive· limited edition· buzzworthy· online only
$50.00

they are so worth the money...These two products worth you to spend money on it...However, this supplement worth me to spend five minutes to recommend it to you...Murad Pure Skin Supplements have been part og my beauty regimen for over a year--I noticed much improvement with my adult acne a little after my third month by taking one tablet each morning and night
Which skin type is it good for?
✔ Oily
✔ Combination

What it is:
A bottle of Internal Skincare® supplements for non-cystic acne-prone skin that provide the nutrients needed to support the body's natural defense against blemish-producing toxins.

Solutions for:
- Acne and blemishes
- Pores
- Oiliness

If you want to know more…
Murad's supplements are designed to improve the overall health of the skin. They are formulated with ingredients that help reduce non-cystic blemishes and provide internal defense against breakouts for clearer, healthier-looking skin.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Size 2.0 oz/ 60 mL · ITEM 2376200
exclusive· limited edition· buzzworthy· online only
$54.00

What it is: A highly potent, feather-light serum that goes on easily and absorbs quickly.

Hair Type: Straight, Wavy, Curly, and Coily

Hair Texture: Fine, Medium, and Thick

Hair Concerns:
- Dryness
- Color Safe
- Flaky/Dry Scalp

Key Benefits:
- Soothes
- Rebalances
- Nourishes

Formulation: Serum

Highlighted Ingredients:
- Biomimetic Peptide: Enhances hair health.
- Olive-Oil-Derived Ceramides: Improve overall scalp health and nutrition.
- Specialty Watercress and Indian Cress Extracts: Support cell turnover.

Ingredient Callouts: Free of sulfates SLS and SLES, parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, oxybenzone, coal tar, hydroquinone, triclosan, and triclocarban. This product is also vegan, cruelty-free, and gluten-free, and comes in recyclable packaging.

What Else You Need to Know: Topical Scalp Supplement™ ­provides the scalp and hair with nutrients using pure Alpha Keratin 60ku®, B vitamins, peptides, and prebiotic activity. The result: a healthy scalp for strong, vibrant, and youthful hair. This serum is ideal for all hair and scalp types and is safe for color-treated and chemically treated hair.

Clinical Results: In a consumer-perception study conducted on 50 respondents:
- 92% of women said their scalp felt healthier, less irritated, and nourished after just 1 week
- After 2 weeks, 95% of women claimed their hair felt and looked healthier and more manageable
- After 1 month 95% women said their scalp felt soothed and less dry
ITEM 1650191
exclusive· limited edition· buzzworthy· online only
$60.00

This seems to work...I think it may be too soon to see a huge change in my wrinkles, but I think it is improving, a subtle change
Beauty Benefit: Hydration

What it is: A rare lingonberry seed oil supplement to help rejuvenate skin and reduce wrinkles.

What it tastes like: No flavor

How to use: Take three soft gels daily with food

Dosage: Three soft gels per day

When to expect results: Four to six weeks

What Else You Need to Know: HUM searched the world for a rejuvenating ingredient and found it in the Finnish Wild. Arctic Repair’s unique balance of omegas and demonstrated in a clinical study to reduce wrinkles, while increasing skin hydration and elasticity. It’s made of rare lingonberry seed oil, hence the limited yearly supply.

Clinical Results: In a 2012 study on the effects of lingonberry seed oil on skin, tested on 30 women for 3 months:
- Significant improvement in skin hydration
- Significant improvement in skin density and elasticity
- Significant decrease in skin roughness

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
ITEM 2122950
exclusive· limited edition· buzzworthy· online only
$64.00

What it is:
A vegan, non-GMO, antioxidant-packed probiotic and prebiotic designed to give your body a daily dose of "good" bacteria.*

What it does:
RMS Beauty’s Within Probiotic + Prebiotic Dietary Supplement supports a healthy immune system and digestive function, as well as skin, hair, and nail health. It also helps reduce discomfort from bloating and gas by supporting healthy microflora in the gut. A healthy gut containing high levels of good bacteria allows food to be broken down more efficiently, helping the absorption of key vitamins and nutrients.*

What else you need to know:
Within Probiotic + Prebiotic is gluten-free, GMO-free, and 100 percent vegan. It contains no milk, soy, wheat, shellfish, egg, tree nuts, peanuts, corn, or animal by-products.

This formula contains 25 billion CFU per serving of good bacteria made with a 50 percent overage at time of manufacture to ensure 25 billion CFU potency in an ISO/IEC 17025:2005 accredited lab.

These supplements are delayed-release capsules, packaged in a recyclable, dark glass bottle to promote shelf stability. Because they don’t require refrigeration, they are great for travel.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Clean at Sephora
Clean at Sephora is formulated without a list of over 50 ingredients, including sulfates (SLS and SLES), parabens, phthalates, and more. For the full list, check out the Ingredients tab.
ITEM 2122927
exclusive· limited edition· buzzworthy· online only
$64.00

What it is:
An enzyme supplement to support optimal digestion and absorption of nutrients from each meal.*

What it does:
This supplement includes 17 enzymes specifically designed for a women’s diet. It’s meant to aid in the digestion of fats, carbs, grains, dairy, fiber, protein, vegetables, and sugars (including alcohol). Taking these enzymes consistently may help diminish the visible signs of aging, so you’ll not only look better, but feel better too. This no-refrigeration-required formula is supercharged with superoxide dismutase, the enzyme that protects against free radicals, providing anti-aging and antioxidant benefits.*

This set contains:
- 90 x Capsules

What else you need to know:
This women's digestive enzyme supports natural reduction in gas and bloating after a meal, as well as energy levels, nutrient absorption from food, healthy digestion of gluten protein, and the breakdown of otherwise difficult-to-digest food.* It is gluten-free and GMO-free, and contains no milk, soy, wheat, shellfish, egg, tree nuts, peanuts, corn, or animal by-products.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Clean at Sephora
Clean at Sephora is formulated without a list of over 50 ingredients, including sulfates (SLS and SLES), parabens, phthalates, and more. For the full list, check out the Ingredients tab.
ITEM 2162436
exclusive· limited edition· buzzworthy· online only
$78.00

Tastes good as well...Quick and Easy Nutrients...I would recommend this supplement, especially if you know you're not getting enough nutrients in your body...I find it difficult to get a lot of nutritional substance in my diet daily and this product makes it easy and quick
Beauty Benefit: Skin Health

What it is: A delicious, vegan tablet of eight real greens and only 10 calories to support healthy aging, better circulation, and antioxidants for glowing skin.

What it tastes like: Lemon-Lime

How to use: Drop one tablet in eight ounces of water or liquid of your choice.

Dosage: One tablet

What Else You Need to Know: Each tablet contains eight essential greens that can be hard to eat during a busy day: spinach, wheatgrass, kale, blue green algae, spirulina, chlorella, barley grass, and aloe vera. These ingredients are real greens, not vitamins or extracts, so you can drink a skin-brightening green juice, anytime.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
ITEM 1159961
exclusive· limited edition· buzzworthy· online only
$95.00

What it is:
Vitamin supplements that work from the inside out to support clear skin.

What it is formulated to do:
The Perricone MD Skin Clear Nutritional Support System program is one of the most advanced and comprehensive dietary supplements available to help improve the appearance of problem skin. It's specifically formulated to improve skin's clarity while providing toning benefits and improving skin's texture. This program also helps to support a healthy immune system and provide antioxidant protection.

What else you need to know:
Each box contains 30 packets of once-daily supplements; daily packet contains:
- B Complex + Vitamin C
- Evening Primrose Oil (EPO)
- Ascorbyl Palmitate
- Omega-3
- Ala+DMAE+Chromium+Zinc
- Tocospan Vitamin
- Calcium+Magnesium+Vitamin D supplement
ITEM 1160068
exclusive· limited edition· buzzworthy· online only
$210.00

What it is:
A program designed to promote healthy weight loss and maintenance.

What it is formulated to do:
Perricone Health Weight Management Dietary Supplements are a perfectly dosed daily program of nutrients designed to enhance healthy weight loss and maintenance. It assists in increasing metabolism and decreasing body fat while boosting energy levels and satisfying the appetite. Targeted nutritional supplements are an essential part of Dr. Perricone's 3-tier approach to a healthy body and beautiful skin and the supplements are organized for convenience into morning, noon, and evening packets.

This set contains:
90 packets with each packet containing: 3 Softgels, 4 Capsules, and 1 Caplet.
- Perricone Prescription™ Super Antioxidant Formula
- Tyrosine and Alpha Lipoic Acid
- L-Carnitine
- DMAE
- Acetyl L-Carnitine
- CLA (Conjugated Linoleic Acid)
- Evening Primrose Oil (EPO)
- CO-Q10

Size 1.5 oz/ 42.5 g · ITEM 2008688
exclusive· limited edition· buzzworthy· online only
$38.00

What it is:
An adaptogenic blend of transformative superherbs and pearl that help combat the effects of stress to expand your beauty, luster, and glow from within.*

If you want to know more…
This formula contains ingredients that help the body to preserve collagen protein*, enhance elasticity of the skin*, and cope with stress* with a tart berry flavor. Moon Dusts are fresh and potent with intensely herbal flavors. You will feel the effects and your palate will evolve. Intensity has its benefits.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

What else you need to know:
Adaptogens are plants, mushrooms, and minerals that have traditionally been used to help the body manage stress, whether the source is mental, physical, or emotional. Adaptogens work to restore balance in the adrenal, endocrine, nervous, and immune systems, reducing the impacts of stress (aging, exhaustion, anxiety) on body, beauty, and consciousness from the inside out.

Moon Dust does not fully dissolve. Use a blender, aerolatte, or shaker to thoroughly incorporate, then let the Dust settle.

This product is cruelty-free and gluten free.
Size 1.5 oz/ 42.5 g · ITEM 2008720
exclusive· limited edition· buzzworthy· online only
$38.00

What it is: An adaptogenic blend of lusty superherbs and Shatavari that helps combat the effects of stress to ignite your creative energy, in and out of the bedroom.*

If you want to know more…
This formula contains ingredients that help support the body during stress*, provide energy, vitality, and wellbeing*, and boost libido* with a smoky, chocolaty flavor. Moon Dusts are fresh and potent with intensely herbal flavors. You will feel the effects and your palate will evolve. Intensity has its benefits.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

What else you need to know:
Adaptogens are plants, mushrooms, and minerals that have traditionally been used to help the body manage stress, whether the source is mental, physical, or emotional. Adaptogens work to restore balance in the adrenal, endocrine, nervous, and immune systems, reducing the impacts of stress (aging, exhaustion, anxiety) on body, beauty, and consciousness from the inside out.

Moon Dust does not fully dissolve. Use a blender, aerolatte, or shaker to thoroughly incorporate, then let the Dust settle.

This product is cruelty-free, gluten free, and vegan

Clean at Sephora
Clean at Sephora is formulated without a list of over 50 ingredients, including sulfates (SLS and SLES), parabens, phthalates, and more. For the full list, check out the Ingredients tab.
Size 1.5 oz/ 42.5 g · ITEM 2008696
exclusive· limited edition· buzzworthy· online only
$38.00

What it is:
An adaptogenic blend of enlightening superherbs and supermushrooms that help combat the effects of stress to align you with the cosmic flow for great achievement.*

If you want to know more…
This formula contains ingredients that help sharpen focus and concentration*, increase mental stamina*, and promote a positive mind and mood.* The taste is herb forward with a botanical bite. Moon Dusts are fresh and potent with intensely herbal flavors. You will feel the effects and your palate will evolve. Intensity has its benefits.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

What else you need to know:
Adaptogens are plants, mushrooms, and minerals that have traditionally been used to help the body manage stress, whether the source is mental, physical, or emotional. Adaptogens work to restore balance in the adrenal, endocrine, nervous, and immune systems, reducing the impacts of stress (aging, exhaustion, anxiety) on body, beauty, and consciousness from the inside out.

Moon Dust does not fully dissolve. Use a blender, aerolatte, or shaker to thoroughly incorporate, then let the Dust settle.

This product is cruelty-free and gluten-free.
Size 1.5 oz/ 42.5 g · ITEM 2008704
exclusive· limited edition· buzzworthy· online only
$38.00

What it is:
An adaptogenic blend of tranquil superherbs and Chamomile Flower that help combat the effects of stress to soothe your tension for deep, nocturnal rest.*

If you want to know more…
This formula contains ingredients that help alleviate the effects of stress and tension* and promote more restful sleep* with notes of sweet, chamomile. Moon Dusts are fresh and potent with intensely herbal flavors. You will feel the effects and your palate will evolve. Intensity has its benefits.

What else you need to know:
Adaptogens are plants, mushrooms, and minerals that have traditionally been used to help the body manage stress, whether the source is mental, physical, or emotional. Adaptogens work to restore balance in the adrenal, endocrine, nervous, and immune systems, reducing the impacts of stress (aging, exhaustion, anxiety) on body, beauty, and consciousness from the inside out.

Moon Dust does not fully dissolve. Use a blender, aerolatte, or shaker to thoroughly incorporate, then let the Dust settle.
This product is cruelty-free, gluten free, and vegan. created with a blend of superherbs and chamomile flower that help combat the effects of stress to soothe your tension for deep nocturnal rest.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Clean at Sephora
Clean at Sephora is formulated without a list of over 50 ingredients, including sulfates (SLS and SLES), parabens, phthalates, and more. For the full list, check out the Ingredients tab.
Size 1.5 oz/ 42.5 g · ITEM 2008738
exclusive· limited edition· buzzworthy· online only
$38.00

Supplements are very personal, of course, and this is likely to be right for some people...As a complementary treatment for ADHD and TBI, though, the mushrooms and adaptogens in Brain Dust are better...I recommend Moon Juice products as a complement to mainstream medicine, not a substitute for it, if you have a diagnosed neurological condition
What it is:An adaptogenic blend of uplifting superherbs and super mushrooms that helps combat the effects of stress to expand peaceful awareness and align you with bliss.*

If you want to know more…
This formula contains ingredients that help promote a positive, relaxed state of mind*, increase resistance to stress, tension, and irritability*, and enhance feelings of emotional wellbeing* with a sweet, nutty flavor. Moon Dusts are fresh and potent with intensely herbal flavors. You will feel the effects and your palate will evolve. Intensity has its benefits.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

What else you need to know:
Adaptogens are plants, mushrooms, and minerals that have traditionally been used to help the body manage stress, whether the source is mental, physical, or emotional. Adaptogens work to restore balance in the adrenal, endocrine, nervous, and immune systems, reducing the impacts of stress (aging, exhaustion, anxiety) on body, beauty, and consciousness from the inside out.

Moon Dust does not fully dissolve. Use a blender, aerolatte, or shaker to thoroughly incorporate, then let the Dust settle.

This formula is organic, cruelty-free, gluten free, and vegan.

Clean at Sephora
Clean at Sephora is formulated without a list of over 50 ingredients, including sulfates (SLS and SLES), parabens, phthalates, and more. For the full list, check out the Ingredients tab.