Best Acne Spot Treatments

Sephora customers often prefer the following products when searching for Best Acne Spot Treatments.

Acne can be a frustrating and confidence-denting skin concern that many of us have experienced at some point. When those pesky pimples pop up, it's important to have effective spot treatments on hand to help combat them. Whether you're dealing with occasional breakouts or persistent blemishes, these acne spot treatments are here to save the day. These targeted solutions are designed to help reduce the appearance of acne, minimize redness, and promote clearer-looking skin.

CLINIQUEAcne Solutions™ Clinical Clearing Gel

ITEM: 1592831

Size: 1 oz/ 30 mL

1.1K Reviews

$46.00

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This is a great spot treatment, especially for cystic acne! It can be pretty drying, so I only use it on emerging spots, while I use the Clinique acne solutions clarifying lotion all over to prevent cystic acne. ...BEST spot treatment! I wear during the day for stubborn spots and it really zaps over night as well! ...great spot treatment for cystic acne...BEST spot treatment

What it is: A topical formula for breakouts with results as good as a leading prescription.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Acne and Blemishes

Formulation: Lightweight Gel

Highlighted Ingredients:
- Salicylic Acid: Clears dead skin cells that can contribute to clogged pores.
- Witch Hazel: Minimizes shine on the skin‘s surface and tightens the appearance of pores.
- Laminaria Saccharina Extract: Helps decrease oil buildup that can lead to breakouts.

Ingredient Callouts: Free of sulfates SLS and SLES, parabens, and phthalates. This product is also gluten-free.

What Else You Need to Know: This formula with salicylic acid helps clear th

$30.00

I am glad I finally decided to buy this acne spot treatment . It smells bad but the scent isn’t overwhelming. ...Very effective acne treatment...Very effective acne treatment, helps the skin to regenerate and eradicate the acnes more quickly.

What it is: An acne treatment gel with 1.5% Salicylic Acid for on-the-spot, targeted treatment––wherever you go.


Skin Type: Normal, Dry, and Oily


Skincare Concerns: Acne and Blemishes, Redness, and Oiliness


Formulation: Gel


Highlighted Ingredients:

- Saw Palmetto: Helps control oil, reduce shine, and prevent breakouts.


What Else You Need to Know: This blemish-fighting formula with saw palmetto and 1.5 percent salicylic acid helps eliminate excess oil that can lead to break outs.

MuradRapid Relief Acne Spot Treatment

ITEM: 1968320

Size: 0.5 oz/ 15 mL

650 Reviews

$35.00

Now this is my go-to acne spot treatment! Consistently effective with daily treatments to help treat acne. ...This is a lifer saver spot treatment. I have been struggling to mask acne for 2 months and tried other expensive spot treatments but didn't work.

Which skin type is it good for?
✔ Oily
✔ Combination

What it is:
A maximum strength two percent salicylic acid gel formula that reduces blemish size and redness in as little as four hours.

Solutions for:
- Acne and blemishes
- Oiliness
- Pores

If you want to know more…
This maximum strength formula contains salicylic acid to exfoliate, clear pores, and smooth skin. Inspired by pine and thyme extracts, a patented complex fights irritants while preserving skin’s healthy balance. The clear gel formula works well under makeup without pilling or peeling to treat blemishes while concealing.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

$54.00

I loved this retinol treatment! I thought the formula was very nice, and it definitely improved my skin. ...If you have very sensitive skin and are very acne prone, the fact this has such a low dose of retinol (.05) is perfect.

What it is: A nightly 0.5% retinoid serum made for all skin types that visibly improves fine lines, dark spots, texture, and tone all while nourishing skin.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Dark Spots, Fine Lines and Wrinkles, and Uneven Texture

Formulation: Lightweight Cream

Highlighted Ingredients:
- 0.5% Retinyl Sunflowerate: Composed of retinol and sunflower seed fatty acids.
- Stevia Extract: Smooths the look of skin and fine lines.
- Mondo Grass Root Extract: Humectant, helps skin hold onto moisture.

Ingredient Callouts: This product is vegan, gluten-free, and cruelty-free.

What Else You Need to Know: This serum includes hardworking

$151.00

Unlike some other retinoid treatments, the Equilibrium Resurfacing Retinoid Treatment does not cause irritation or redness, making it suitable for most sensitive skin types.I have noticed a significant improvement in the overall texture and tone of my skin. ...Love using this treatment and I’m truly amazed by the results. This retinol treatment helps to reduce dark spots and fine line and wrinkles.

What it is: A lightweight resurfacing treatment that boosts clarity and helps visibly even skin texture and tone for more balanced skin with a healthy glow.

Highlighted Ingredients:
- Retinoid, Hexylresorcinol, and Niacinamide: A clinically backed blend that visibly reduces fine lines and wrinkles and diminishes the appearance of dark spots and hyperpigmentation while being gentle to skin.

Ingredient Callouts: Free of parabens and mineral oil. It is also cruelty-free.

What Else You Need to Know: This fast-absorbing treatment is formulated with a blend of a retinoid, hexylresorcinol, and niacinamide to visibly reduce fine lines and wrinkles and diminish the appearance of dark spots and hyperpigmentation. The formula is ef

$79.00

My skin feels hydrated, and my dark spots have faded....Best skincare routine I've ever had...The formula in these products work really well for me, it's brightening and helped a lot with relatively new dark spots. My old dark spots that's been with me for more than a decade are slowly fading away too but obviously it'll take more time.

What it is: A dark spot and discoloration-fighting trio, including an AHA mask, brightening serum, and vitamin C moisturizer, for smooth, even, and glowing skin.


Skin Type: Normal, Dry, Combination, and Oily


Skincare Concerns: Dark Spots, Redness, Dullness


Highlighted Ingredients:

- Vitamin C Ester (Tetrahexyldecyl Ascorbate): Brightening agent and antioxidant.

- Glycolic Acid: Exfoliates and promotes smoother skin.

- Alpha Arbutin: Improves the appearance of uneven skin t

$46.00

I love the the Pre-Show Glow Instant Retexturizing Treatment. I used this product twice a week and can see an improvement in my skin’s dark spots and vibrance. ...The product leaves your skin feeling silky smooth! I have acne prone skin with dark spots and this seems to have improved the spots thus far!

What it is: This one minute 10% AHA treatment clarifies, purifies, brightens and smooths skin by gently clearing dull surface cells to even texture over time.


Skin Type: Normal, Dry, Combination, and Oily


Skincare Concerns: Dark Spots, Dullness, and Uneven Texture


Formulation: Liquid

$79.00

This overnight treatment is a game changer!...I’m so impressed by this overnight treatment. I immediately woke up to brighter, hydrated and a more even skin tone. ...Great overnight treatment for dark spots!...I would definitely recommend it to anyone who wants to brighten dark spots!

What it is: A visibly brightening oil infused with niacinamide and vitamin C to recharge skin’s visible radiance while you sleep—for a glowing look by morning.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Dryness, and Dullness

Formulation: Lightweight Oil

Highlighted Ingredients:
- Vita-Charge™ Brightening Complex: Visibly brightens skin and improves dark spots.
- Lactic and Mandelic Acids: Visibly even skin tone and texture.
- Seaberry, Turmeric, and Ginseng: Replenish and nourish skin.

Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone,

$94.00

This makes it a fantastic option for those with sensitive skin or anyone new to retinol treatments. Overall, the CLINICAL 0.3% Retinol + 2% Bakuchiol Treatment has exceeded my expectations. ...Best retinol in the market!...I also noticed my acne scars looked brighter than before and my pores look visibly smaller which is a huge deal for me!

What it is: A retinol-, bakuchiol-, and peptide-powered formula that supports skin's natural elasticity, reduces the look of lines and wrinkles, and addresses loss of firmness.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Pores, and Loss of Firmness and Elasticity

Formulation: Lightweight Cream

Highlighted Ingredients:
- Retinol 0.3%: Reduces the look of fine lines and wrinkles.
- Bakuchiol 2%: Amplifies retinol's visible effect on skin.
- Peptides: Support natural elasticity and visibly firm skin.

Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal ta

$57.00

Dennis Gross’s Advanced Retinol + Ferulic Perfectly Dosed Retinol Treatment is a skincare game-changer. LAfter four weeks, I noticed reduced dark spots, smoother texture, and increased radiance. ...Wow! This retinol treatment is a game-changer. My fine lines and dark spots are visibly reduced, and my skin texture is smoother.

What it is: A targeted, overnight peel treatment to reduce fine lines, improve uneven tone and texture, and restore hydration for a radiant, healthy-looking complexion.


Skin Type: Normal, Dry, Combination, and Oily


Skincare Concerns: Dark Spots, Fine Lines and Wrinkles, and Uneven Texture


Highlighted Ingredients:

- Retinol: A vitamin A derivative that supports collagen production while visibly reversing signs of photo-aging, improving fine lines and wrinkles, addressing UV-induced free-radical damage, reducing blemish-causing sebum, and fading dark spots.

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“It’s my daughters & my favorite go to for acne / pimple SO WORTH THE PRICE & a tiny tiny bit is all you need”
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“Worked for pus filled pimples only. It didn’t really help with fading the dark spot the pimple leaves behind, but it didn’t make sure the pimples go away faster than normal”
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“This is a great product for oily and combo skin. I have combo skin so when I get acne, I’m always worried about products drying out my skin”
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“I've used at least a dozen different treatments, but Ever Eden's has been the best by far”
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“I’ve tried so many things for my ongoing acne, including Benzoyl Peroxide and this is the only product that i see a significant difference in my breakouts even after just a night of wear”
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“I cut them up into smaller portions and use for larger cyst breakouts on my chin and jawline to help with my cystic hormonal acne”

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