Dr. Idriss
The Depuffer Soothing Roll-On Treatment Serum for Facial Puffiness
Highly rated by customers for: , ,

$54.00or 4 payments of $13.50 with or
Size: 1.35 oz
Standard size
Mini size
Highlights
Niacinamide
Oil Free
Good for: Redness
Good for: Dryness
allure 2023 Best of Beauty Award Winner
Fragrance Free
About the Product
Item 2647576
Only at Sephora
What it is: A roll-on serum, with centella asiatica and niacinamide, shown to relieve redness and puffiness.
Skin Type: Normal, Dry, Combination, and Oily
Skincare Concerns: Dark Spots, Redness, Puffiness
Formulation: Lightweight Gel
Highlighted Ingredients:
- Arnica: Reduces the look of swelling.
- Centella Asiatica: Relieves redness.
- Niacinamide: Soothes and restores skin's moisture barrier.
Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, sulfates SLS & SLES, triclocarban, triclosan, and contains less than one percent synthetic fragrance. It is also gluten-free and cruelty-free.
What Else You Need to Know: This serum contains active ingredients that deliver short- and long-term depuffing, redness-reducing results. The serum’s action is mirrored in that of the cooling roller, which offers short-term depuffing by lymphatic drainage. It was developed by board-certified dermatologist Dr. Idriss (@shereeneidriss).
Clinical Results: In an independent clinical study and consumer-perception study of 26 subjects who used The Depuffer Redness Reducing + Depuffing Roll-On Serum for 5 minutes each day for 4 weeks:
- 92% of users reported The Depuffer soothed signs of irritation
- 88% of users reported a reduction in signs of redness
Skin Type: Normal, Dry, Combination, and Oily
Skincare Concerns: Dark Spots, Redness, Puffiness
Formulation: Lightweight Gel
Highlighted Ingredients:
- Arnica: Reduces the look of swelling.
- Centella Asiatica: Relieves redness.
- Niacinamide: Soothes and restores skin's moisture barrier.
Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, sulfates SLS & SLES, triclocarban, triclosan, and contains less than one percent synthetic fragrance. It is also gluten-free and cruelty-free.
What Else You Need to Know: This serum contains active ingredients that deliver short- and long-term depuffing, redness-reducing results. The serum’s action is mirrored in that of the cooling roller, which offers short-term depuffing by lymphatic drainage. It was developed by board-certified dermatologist Dr. Idriss (@shereeneidriss).
Clinical Results: In an independent clinical study and consumer-perception study of 26 subjects who used The Depuffer Redness Reducing + Depuffing Roll-On Serum for 5 minutes each day for 4 weeks:
- 92% of users reported The Depuffer soothed signs of irritation
- 88% of users reported a reduction in signs of redness
-Arnica: Reduces the look of swelling.
-Centella Asiatica: Relieves redness.
-Niacinamide: Soothes and restores skin's moisture barrier.
Water/Aqua/Eau, Niacinamide, Glycerin, Dimethicone, Pentylene Glycol, Butylene Glycol, Propanediol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Squalane, Arnica Montana Flower Extract, Centella Asiatica Leaf Extract, Fraxinus Excelsior Bark Extract, Agastache Mexicana Flower/Leaf/Stem Extract, Avena Sativa (Oat) Kernel Extract, Camellia Sinensis Leaf Extract, Hydroxyphenyl Propamidobenzoic Acid, Maltodextrin, Dimethicone Crosspolymer, Silanetriol, Sorbitan Isostearate, Polysorbate 60, Caprylyl Glycol, Hexylene Glycol, Ethylhexylglycerin, Phenoxyethanol.
-Centella Asiatica: Relieves redness.
-Niacinamide: Soothes and restores skin's moisture barrier.
Water/Aqua/Eau, Niacinamide, Glycerin, Dimethicone, Pentylene Glycol, Butylene Glycol, Propanediol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Squalane, Arnica Montana Flower Extract, Centella Asiatica Leaf Extract, Fraxinus Excelsior Bark Extract, Agastache Mexicana Flower/Leaf/Stem Extract, Avena Sativa (Oat) Kernel Extract, Camellia Sinensis Leaf Extract, Hydroxyphenyl Propamidobenzoic Acid, Maltodextrin, Dimethicone Crosspolymer, Silanetriol, Sorbitan Isostearate, Polysorbate 60, Caprylyl Glycol, Hexylene Glycol, Ethylhexylglycerin, Phenoxyethanol.
Suggested Usage:
-Apply anytime to clean, dry skin.
-Twist the roller "on," gently squeeze, and glide over your skin to distribute a small amount of serum.
-Twist "off," and continue rolling to your heart’s content.
-Gently roll serum outward and upward when applying under eyes.
-Pat in any excess. Allow to dry before applying other skincare products or makeup.
-Apply anytime to clean, dry skin.
-Twist the roller "on," gently squeeze, and glide over your skin to distribute a small amount of serum.
-Twist "off," and continue rolling to your heart’s content.
-Gently roll serum outward and upward when applying under eyes.
-Pat in any excess. Allow to dry before applying other skincare products or makeup.
Use It With
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At Dr. Idriss, we eliminate the B.S. and fearmongering, focusing solely on high-performance formulas and ingredients used at the most effective levels for your skin. Our products are rooted in science, drawing from Dr. Idriss’ in-office experience, real results from patients, and clinical testing.

