Dermalogica
Phyto Nature E² Exosome + Exfoliation Leave-On Treatment Serum for Smoother Texture, Brighter Skin & Wrinkles
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$229.00or 4 payments of $57.25 with 
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Size: 3.4 oz/100 mL
Standard size
About the Product
Item 2951127
What it is: A regenerative exosome and enzyme formula that resurfaces to accelerate cellular renewal, supporting the skin’s natural surface-renewal process.
Skin Type: Normal, Combination, and Oily
Skincare Concerns: Fine Lines and Wrinkles and Uneven Texture
Formulation: Serum
Highlighted Ingredients:
- Regenerative Exosome Blend: Diminishes the appearance of fine lines and wrinkles.
- Pumpkin Enzyme: Exfoliates to reveal brighter-looking, smoother skin daily.
- Bio-Fermented Acetyl Glucosamine: Hydrates and provides antioxidant protection.
- Botanical Blend with Phyto Glycogen and Prickly Pear: Visibly brightens and smooths.
Ingredient Callouts: Free of mineral oil.
What Else You Need to Know: This advanced, daily leave-on formula promotes the skin’s natural surface-renewal process with exosomes and enzyme phytoactives. Pumpkin enzyme exfoliates by breaking the bonds of dead cells at the skin’s surface, revealing brighter-looking, smoother skin every day. The Regenerative Exosome Blend with turmeric stem cells and Acacia Senegal extract acts on multiple layers of the skin’s surface, diminishing the appearance of fine lines and wrinkles. A botanical blend with phyto glycogen and prickly pear boosts the skin’s natural exfoliation capacity to visibly brighten and smooth. Bio-fermented acetyl glucosamine hydrates and provides antioxidant protection against free radicals.
Clinical Results: Based on in-vitro testing, when using Phyto Nature E2 versus untreated skin:
- Improves natural regeneration by 86%
Based on a reduction in visible signs of skin aging in an independent clinical study with 32 subjects, 2 applications/day:
- Visibly diminishes fine lines and wrinkles in 2 weeks
Based on an 8-week independent clinical study with 32 subjects, 2 applications/day, consumer-perception results included:
- Skin looks and acts younger after 1 use
Skin Type: Normal, Combination, and Oily
Skincare Concerns: Fine Lines and Wrinkles and Uneven Texture
Formulation: Serum
Highlighted Ingredients:
- Regenerative Exosome Blend: Diminishes the appearance of fine lines and wrinkles.
- Pumpkin Enzyme: Exfoliates to reveal brighter-looking, smoother skin daily.
- Bio-Fermented Acetyl Glucosamine: Hydrates and provides antioxidant protection.
- Botanical Blend with Phyto Glycogen and Prickly Pear: Visibly brightens and smooths.
Ingredient Callouts: Free of mineral oil.
What Else You Need to Know: This advanced, daily leave-on formula promotes the skin’s natural surface-renewal process with exosomes and enzyme phytoactives. Pumpkin enzyme exfoliates by breaking the bonds of dead cells at the skin’s surface, revealing brighter-looking, smoother skin every day. The Regenerative Exosome Blend with turmeric stem cells and Acacia Senegal extract acts on multiple layers of the skin’s surface, diminishing the appearance of fine lines and wrinkles. A botanical blend with phyto glycogen and prickly pear boosts the skin’s natural exfoliation capacity to visibly brighten and smooth. Bio-fermented acetyl glucosamine hydrates and provides antioxidant protection against free radicals.
Clinical Results: Based on in-vitro testing, when using Phyto Nature E2 versus untreated skin:
- Improves natural regeneration by 86%
Based on a reduction in visible signs of skin aging in an independent clinical study with 32 subjects, 2 applications/day:
- Visibly diminishes fine lines and wrinkles in 2 weeks
Based on an 8-week independent clinical study with 32 subjects, 2 applications/day, consumer-perception results included:
- Skin looks and acts younger after 1 use
-Regenerative Exosome Blend: Diminishes the appearance of fine lines and wrinkles.
-Pumpkin Enzyme: Exfoliates to reveal brighter-looking, smoother skin daily.
- Bio-Fermented Acetyl Glucosamine: Hydrates and provides antioxidant protection.
- Botanical Blend with Phyto Glycogen and Prickly Pear: Visibly brightens and smooths.
Water/Aqua/Eau, Lactobacillus/Pumpkin Ferment Extract, Propanediol, Lactococcus Ferment Lysate, Ethoxydiglycol, Hydrolyzed Soy Protein, Acetyl Glucosamine, Hydroxyacetophenone, Lactic Acid, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Helianthus Annuus (Sunflower) Seed Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Citrus Limon (Lemon) Peel Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Salvia Sclarea (Clary) Oil, Pyrus Malus (Apple) Fruit Extract, Viola Odorata Leaf Extract, Acacia Senegal Gum Extract, Curcuma Longa (Turmeric) Root Extract, Mucor Miehei Extract, Lavandula Spica (Lavender) Flower/Leaf/Stem Extract, Rosmarinus Officinalis (Rosemary) Leaf Oil, Litsea Cubeba Fruit Oil, Camellia Japonica Flower Extract, Glycerin, Mentha Piperita (Peppermint) Oil, Butylene Glycol, Lactobacillus Ferment, Glycogen, Urea, Caprylyl Glycol, Phospholipids, Glucosamine HCl, Xanthan Gum, PEG-40 Hydrogenated Castor Oil, 1,2-Hexanediol, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Citric Acid, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Sodium Chloride, Sodium Citrate, Disodium EDTA, Sodium Benzoate, Potassium Sorbate, Limonene, Linalool, Citral.
-Pumpkin Enzyme: Exfoliates to reveal brighter-looking, smoother skin daily.
- Bio-Fermented Acetyl Glucosamine: Hydrates and provides antioxidant protection.
- Botanical Blend with Phyto Glycogen and Prickly Pear: Visibly brightens and smooths.
Water/Aqua/Eau, Lactobacillus/Pumpkin Ferment Extract, Propanediol, Lactococcus Ferment Lysate, Ethoxydiglycol, Hydrolyzed Soy Protein, Acetyl Glucosamine, Hydroxyacetophenone, Lactic Acid, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Helianthus Annuus (Sunflower) Seed Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Citrus Limon (Lemon) Peel Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Salvia Sclarea (Clary) Oil, Pyrus Malus (Apple) Fruit Extract, Viola Odorata Leaf Extract, Acacia Senegal Gum Extract, Curcuma Longa (Turmeric) Root Extract, Mucor Miehei Extract, Lavandula Spica (Lavender) Flower/Leaf/Stem Extract, Rosmarinus Officinalis (Rosemary) Leaf Oil, Litsea Cubeba Fruit Oil, Camellia Japonica Flower Extract, Glycerin, Mentha Piperita (Peppermint) Oil, Butylene Glycol, Lactobacillus Ferment, Glycogen, Urea, Caprylyl Glycol, Phospholipids, Glucosamine HCl, Xanthan Gum, PEG-40 Hydrogenated Castor Oil, 1,2-Hexanediol, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Citric Acid, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Sodium Chloride, Sodium Citrate, Disodium EDTA, Sodium Benzoate, Potassium Sorbate, Limonene, Linalool, Citral.
Suggested Usage:
-Apply to clean skin.
-Allow to absorb, then follow with the rest of your skincare routine.
-Use twice daily.
How to Recycle:
-Ensure bottle is as empty as possible.
-Visit any Sephora store and discard your unbagged empties in the Pact bin—it’s usually near the checkout.
-Apply to clean skin.
-Allow to absorb, then follow with the rest of your skincare routine.
-Use twice daily.
How to Recycle:
-Ensure bottle is as empty as possible.
-Visit any Sephora store and discard your unbagged empties in the Pact bin—it’s usually near the checkout.
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Dermalogica is a professional-grade skin care brand founded by a skin therapist, so we know how to create skin care solutions that work. Our mission has always been the same: develop innovative products and services that actively improve skin health. Based in Los Angeles, our products are made in the USA and sold in more than 80 countries worldwide. We are cruelty free, certified vegan and our formulas have been clean since 1986. As of 2020, all paper and cartons we use are FSC certified to be sustainable for forests.