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Skin Barrier Repair Serums

Sephora customers often prefer the following products when searching for Skin Barrier Repair Serums.

Achieve a healthy, radiant complexion with this collection of skin barrier repair serums. Designed to nourish and strengthen your skin's protective barrier, these serums work tirelessly to restore moisture, soothe irritation, and promote a smoother, more even-toned complexion. Whether you're battling dryness, sensitivity, or environmental stressors, this range of skin barrier repair serums is here to support your skin's natural defenses and leave you with a glowing, revitalized visage.

La MerMini The Concentrate Serum for Barrier Repair and Hydration

ITEM: 2384022

Size: 0.5 oz/ 15 mL

613 Reviews

$303.00

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As with all of the La Mer products that contain their miracle broth I think it is a great serum that helps the skin barrier. It is also so good for the redness and the skin feels soft and smooth. ...This smooths the skin barrier leaving behind velvety soft skin and a beautiful lit from within glow!

What it is: A mini-size velvety serum to help rebuild and protect your skin’s natural barrier with the concentrated Miracle Broth™ to help visibly calm redness and inflammation.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines/Wrinkles, Dryness, and Redness

Formulation: Liquid

Highlighted Ingredients:
- Stabilizing Ferment: Marine-sourced ferment visibly strengthens irritated skin.
- Concentrated Miracle Broth™: La Mer's super-concentrated form of cell-renewing Miracle Broth™ helps calm the look of redness and other signs of inflammation.
- Lime Tea Concentrate: Antioxidants protect skin from inflammation from environmental stressors.

$575.00

The concentrate from Lamer is a very velvety-textured serum that focuses on strengthening the skin barrier protecting it from inflammation. ...LA MER THE CONCENTRATE is a barrier building antioxidant powerhouse serum. The serum feels velvety and luxurious.

What it is: A potent barrier serum to strengthen, stabilize, and soothe skin against daily irritants.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Dryness, and Dullness

Formulation: Serum

Highlighted Ingredients:
- Concentrated Miracle Broth™: Powerhouse elixir calms the look of redness while energizing renewal.
- Lime Tea Concentrate: Proprietary antioxidant, neutralizes free radicals to protect skin.
- The Stabilizing Ferment: Proprietary ferment supports fragile, irritated skin.

Ingredient Callouts: Free of parabens, phthalates, and sulfates SLS & SLES.

What Else You Need to Know: Antioxidant-rich serum defends skin ag

$145.00

I did not find this product (or the cream for that matter) anymore effective than using a Cerave cream for skin barrier repair. This serum absorbs quickly, has a slight scent but that must be from the ingredients- not a pleasant fragrance. ...Ceramide serum for barrier repair. Lightweight and non-greasy.

What it is: A lightweight, fast-absorbing serum formulated to support sensitized skin and its protective barrier.

Skin Type: Normal and Dry

Skincare Concerns: Redness and Dryness

Formulation: Lightweight Serum

Highlighted Ingredients:
- Peptide Complex and Ceramides: Relieve redness and irritation while working to support skin’s protective barrier.
- Cucumber Seed Oil: Calms and soothes.
- Tasmannia Lanceolata Fruit Extract: Works to calm skin.

$77.00

Perfect barrier repair serum...For that reason it’s great day or night. This is the perfect barrier repair serum. Also love the packaging!...Amazing for Skin Barrier Repair...This serum is really good for repairing the skin barrier !

What it is: A high-potency serum with 10 potent, active ingredients such as niacinamide and peptides clinically shown to visibly plump, firm, and reduce fine lines.


Skin Type: Normal, Dry, Combination, and Oily


Skincare Concerns: Fine Lines and Wrinkles, Loss of Firmness and Elasticity, and Dryness

$68.00

Great barrier repair product...This is a really great soothing and moisturizing serum. I’m currently using tretinoin and my skin is sensitized and peeling a bit and this has been a great addition to my routine to soothe and help repair my skin barrier while my skin adjusts. ...Barrier Repair in a Bottle...Loved this product so much. helped repair my skin barrier when it was severely damaged from over exfoliating.

What it is: A creamy, supercharged serum that visibly restores the skin barrier to calm sensitivity, intensely hydrate, and support the skin microbiome.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Dryness, and Dullness

Formulation: Lightweight Serum

Highlighted Ingredients:
- Hydrating Triple-Lipid Complex: Skin-similar blend that restores ceramide and fatty acid levels.
- Visibly Plumping Seaweed Hyaluronate Blend: Small particles that intensely hydrate for dewy, glass-like skin.
- Peony Root Complex: Supports the skin barrier and visibly enhances radiance.

Ingredient Callouts: This product is vegan, gluten-free, and cruelty-free.

$62.00

What it is: A concentrated milky hydrating serum with seven barrier benefits in one drop for intense hydration, and dewy, stronger, makeup-optional skin.

Skin Type: Normal, Dry, and Combination

Skincare Concerns: Dryness, Dullness, and Redness

Formulation: Liquid

Highlighted Ingredients:
- Ectoin (Known as the "Stress Protection Molecule") 7%: Reduces water loss, binds moisture, and strengthens the barrier.
- 7 Forms of Hyaluronic Acid: Provide antioxidant defense and intense multilevel hydration.
- Glycogen: Locks in moisture and supports a healthy barrier.

Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil

$105.00

What it is: A serum, infused with five peptides at levels clinically shown to support skin's natural collagen, to help address visible signs of tech-neck and age.

Highlighted Ingredients:
- Five Clinically Proven Peptides (9% Blend): Support skin's natural collagen production.
- Niacinamide (Vitamin B3): Helps to support skin's natural barrier.
- Rosewater: Helps to soothe thin, delicate neck skin.

What Else You Need to Know: The Neck Serum is a clean, effective emulsion with five clinically proven peptides designed to support skin's natural collagen production. It is also designed to address the look of multiple signs of tech-neck and age. The neck area feels firm and looks lifted.

$58.00

What it is: A serum that smooths skin, reduces the look of puffiness, and supports a healthy moisture barrier.
Skin Type: Normal, Dry, and Combination

Skincare Concerns: Loss of Firmness and Elasticity, Dullness, and Puffiness

Formulation: Serum

Highlighted Ingredients:
- BIO-PDRN: Supports skin's moisture barrier.
- Caffeine: Visibly reduces puffiness and energizes tired skin.
- Peptide: Improves the look of firmness and elasticity.

Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, sulfates SLS & SLES, triclocarban, triclosan

$73.00

It does offer some moisture and skin barrier repair but I wasn’t impressed with how it did with the redness claims....Overall, a reliable choice for addressing redness and supporting skin barrier repair.

What it is: A potent face serum with soothing cica complex and allantoin to quickly soothe the skin barrier and reduce redness for healthier-looking skin.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Dryness and Redness

Highlighted Ingredients:
- Cica Complex (Centella Asiatica): Deeply soothes skin.
- Allantoin: Supports skin’s barrier.

Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, sulfates SLS & SLES, triclocarban, triclosan, and contains less than one percent synthetic fragrance. It is also gluten-free.

What Else You Need to Know: This fragrance-free, lightweight face serum was formulated with sensi

$80.00

Great dual chamber product for redness prone skin...It did not completely erase the redness but worked well with makeup for the coverup. I also love the barrier repair cream, especially after a day of retinol, it prevented peeling....I loved the color correcting side as it instantly covered up my redness, and didn’t leave behind any stickiness. The barrier repair serum is a lightweight treatment that helps heal redness over time, and repair the barrier.

What it is: A serum that targets redness and blotchiness immediately and over time.

Skin Type: Dry, Combination, and Oily

Skincare Concerns: Redness and Uneven Texture

Formulation: Lightweight Serum

Highlighted Ingredients:
- Hexapeptide-9 and Biomimetic Peptides: Patented peptide shown to nourish skin barrier and reduce redness.
- 5% Azelaic Acid and Annonasense: Calms effects of stress on skin for visibly less red, bumpy skin.
- Snow Mushroom and Centella Stem Cells: Provide a boost of hydration and support skin barrier.

Ingredient Callouts: This product is vegan, gluten-free, cruelty-free, and comes in recyclable packaging.

What Else You Need to Know: This is the first hi

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“This is my new go-to body wash! It smells so luxurious and amazing. My skin felt so nourished after using which is so important to me when it comes to body washes”
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“I love using this wrinkle cream. It helps my skin hold moisture, keeps my wrinkles softened and my skin looks brighter”
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“I keep it in my purse for when my dry skin needs a shot of moisture. I can't wait to rock this on summer skin”
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“I have been looking for a water-based serum of Vitamin C since I hate the feeling of sticky and oily on my face and this is such a perfect one for me”
Sunscreen Serums
“I put it on before my makeup and it doesn’t affect how my makeup sits on my skin. The spf is high which is always better and I didn’t notice a lasting sunscreen smell that I’ve noticed when trying some sunscreens”

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