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Sephora customers often prefer the following products when searching for Treatments For Severe Acne.

Browse the top-ranked list of Treatments For Severe Acne below along with associated reviews and opinions.

Size 1 oz · ITEM 1167147
exclusive· limited edition· buzzworthy· online only
$26.00

I win....LOVE IT...Great for acne, but not worth the smell...overall one of the best acne treatments I've tried, acne was diminished and more healed the next day after trying it, still works on dryer patches of acne without any flaking for me personally but could have a more drying affect upon someone less oily than me, overall really good product
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry

What it is:
An effective blemish-fighting acne treatment to minimize pimples, zits, and help prevent future breakouts.

Solutions for:
- Acne/blemishes
- Pores

If you want to know more…
Kate's bestselling EradiKate™ Acne Treatment is specifically formulated with the highest level of sulfur allowed to effectively fight blemishes, reduce acne, and help keep skin free of new breakouts. AHAs are designed to reduce the appearance of enlarged pores while zinc oxide, a natural mineral, provides oil control by absorbing excess sebum. The result is clearer skin that lasts.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
EradiKate Acne Treatment is most effective when applied to affected areas as soon as blemishes or pimples are noticed.

"Do you have a pimple you can feel but can't see? Use EradiKate on the area immediately to help prevent it from surfacing."—Kate Somerville, Founder
Size 2 oz · ITEM 1201748
exclusive· limited edition· buzzworthy· online only
$85.00

My FAV...So good...Use over time seems to have made great improvements to the discoloration on my face from acne scarring and melasma, and the overall condition of my skin....I put this on my face and within seconds my face felt like it was on fire I knew this product was working instantly and you only need to leave it on for a little while (10-30 seconds for sensitive skin and up to 3 minutes for everyone else) I have never had to use a sensitive skin peel or exfoliant but I couldn't handle much more than a minute of this.
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry

What it is:
A dual-action exfoliator that smooths and polishes to reveal a glowing, radiant complexion in as little as one use.

Solutions for:
- Dullness/uneven texture
- Pores
- Dark spots/uneven skin tone

If you want to know more…
”The Hollywood 2-minute facial.” Exfoliate and polish skin with ExfoliKate® Intensive Exfoliating Treatment to reveal a glowing, fresh-from-the-clinic complexion. Kate’s bestselling exfoliator is formulated with face scrubbing natural exfoliants to deep clean clogged pores without over-drying skin. Lactic acid and fruit enzymes— papaya, pineapple, and pumpkin—reveal smooth skin and a brighter, healthier-looking complexion in as little as one use. This signature formula works both physically and enzymatically to deliver safe, dramatic results from the comfort of your home.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
When you use ExfoliKate in the shower, the steam will help to activate the enzymes, making it even more effective. Use with ExfoliKate® Cleanser for optimal results.

"Exfoliation is such an important step in maintaining healthy skin, no matter what the weather is. Oils and impurities become trapped under the skin and exfoliation is key."—Kate Somerville

Research results:
Results based on an independent clinical study:
After just 1 use:
- 94% of women tested showed highly significant improvement in skin texture
- 97% of women tested showed highly significant improvement in the appearance of pores
- 100% of women tested showed highly significant improvement in the appearance of crow’s feet, fine lines, and wrinkles

After 4 weeks:
- 100% of women tested showed highly significant improvement in the appearance of skin texture, pores, crow’s feet, fine line, and wrinkles
Size 4 oz/ 120 mL · ITEM 1906106
exclusive· limited edition· buzzworthy· online only
$38.00

It's ok...Love it...Helped especially with my hormonal acne....While placing an order on Sephora, there was a code for a free deluxe sample fo this, so I thought I would give it a try and get it for him.
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination

What it is:
A daily foaming acne cleanser that promotes visibly clearer skin without drying.

Solutions for:
- Acne and blemishes
- Oiliness
- Pores

If you want to know more…
This powerful, medicated cleanser delivers a luxuriously whipped texture and three percent sulfur to address acne and blemishes, draw out impurities, and target congested pores. Honey and rice bran extracts calm redness, while natural oat extract addresses excess sebum. With continued use, this gentle, yet effective daily cleanser leaves skin clearer with visibly minimized pores.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates
Size 1.7 oz/ 50 mL · ITEM 2070944
exclusive· limited edition· buzzworthy· online only
$44.00

Love it...LOVE IT!...Outsmart your acne!...use the Murad Outmart Acne Badge treatment for a week without interruption and the results were favorable and visible in a short time.
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Sensitive

What it is:
A powerful treatment with five clinically proven acne-clearing acids to clear existing acne and help prevent future breakouts.

Solutions for:
- Acne
- Oiliness
- Pores

If you want to know more…
This medicated lightweight gel serum is clinically proven to reduce overall acne in just one week. Salicylic acid combines with lysophosphatidic, hydroxydecanoic, sebacic, and glycolic acids in penta-acid technology to clear skin of acne-causing bacteria, oiliness, and blackheads while minimizing dryness and irritation.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
Five acids. Clear skin. Proprietary penta-acid technology is salicylic acid combined with lysophosphatidic, hydroxydecanoic, sebacic, and glycolic acids to reduce pimples, blackheads, and whiteheads. This product is non-irritating, non-drying, and free of gluten, alcohol, and animal-derived ingredients.

"I have seen many patients develop a tolerance to prescription acne treatments, and when they stop working, it’s devastating. Treating acne demands a more holistic approach that includes lifestyle, nutrition, and advances in topical skincare. I developed Outsmart Acne™ Clarifying Treatment to be used as part of a whole-person regimen to help skin stay consistently clear."—Howard Murad, M.D., FAAD

Murad is cruelty-free, and is proud to deliver high-performance formulas that are tested on people, not animals.

Research results:
Clinically tested by an independent laboratory and proven safe for sensitive skin.

In clinical expert grading:
- 96% of subjects had reduced pimples, blackheads, and whiteheads in just 1 week
Size 2 oz · ITEM 1694173
exclusive· limited edition· buzzworthy· online only
$54.00

Love it!...Love This...I don't have severe acne, it's mild....It doesn't have a super offensive oder and it's a little drying (to be expected as it's a acne clearing mask) but my skin feels nowhere near as tight as like when I use a Glamglow mask.
What it is:
An innovative, gel-cream mask that helps clear acne breakouts, dissolve impurities, and minimize the appearance of pores without over-drying skin.

What it is formulated to do:
EradiKate™ Mask Foam-Activated Acne Treatment gently exfoliates dead skin cells and helps unclog pores while sulfur reduces the appearances and helps prevent pimples, zits, and future breakouts. Within minutes Kate’s unique foam-activated technology penetrates to help dissolve impurities and dirt, and address oily skin. An advanced botanical complex of boswellia serrata, honey extracts, and rice bran work to calm and soothe skin. Use this mask with Kate Somerville’s bestselling EradiKate Acne Treatment for an acne regimen that promotes a clearer complexion.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
This product is a CEW Beauty Insider Award winner for Best Acne Treatment in Prestige.

Research results:
In an independent clinical study after just 1 week:
- Women showed an 88% reduction in the number of blackheads
- Women showed a 55% reduction in the number of whiteheads
- 100% of women showed a reduction in pore size

After 4 weeks:
- Women showed a 100% reduction in the number of blackheads
- Women showed a 86% reduction in the number of whiteheads
- 100% of women showed a reduction in pore size
- 80% of women reported it prevents clogged pores to minimize breakouts
- 77% of women reported it absorbs excess oil
- 87% of women reported skin looked and felt smoother
Size 1 oz/ 30 mL · ITEM 2113777
exclusive· limited edition· buzzworthy· online only
$58.00

Love it!...In love!...I had just ran out of my prescription topical acne medicine that I can't live without, so it was perfect timing to try it out....I have pretty oily skin and gets lot of breakouts and redness around my nose and chin, and after using this for just a few days at night my skin looks a lot more even and no new pimples!
Which skin type is it good for?
✔ Normal
✔ Combination

What it is:
A lightweight, all-over acne treatment, formulated with salicylic acid to reduce and prevent blemishes.

Solutions for:
- Acne and blemishes
- Dullness and uneven texture
- Pores

If you want to know more…
This lightweight, all-over acne treatment clears acne with two percent salicylic acid—the highest percentage allowed. It also contains retinol, which helps smooth the look of skin texture and even the look of skin tone while a blend of soothing ingredients helps balance the skin’s microbiome. This hydrating formula also contains sodium PCA and sodium hyaluronate, which moisturize skin and help offset dryness that could be caused by salicylic acid and/or retinol.

Research results:
In an independent clinical study, after 24 hours/overnight:
- 97% of subjects showed improvement in the appearance of pore size
- 90% of subjects showed improvement in the appearance of skin texture
- Blackheads were significantly improved
- Pustules were significantly improved

After 4 weeks:
- 100% of subjects showed improvement in appearance of pore size
- 100% of subjects showed improvement in the appearance of skin texture
- 79% of subjects showed improvement in whiteheads
Size 2 oz · ITEM 1201763
exclusive· limited edition· buzzworthy· online only
$65.00

LOVE IT...Love it!...My daughter does NOT have an acne problem.......I use a little less than a dime size amount once or twice a week but you can't help but be disappointed that the price to amount ratio seems insane.
What it is:
A delicate exfoliant for sensitive skin.

What it is formulated to do:
Kate Somerville ExfoliKate® Gentle Exfoliating Treatment decongests, detoxifies, and refines skin to reveal a polished, flawless complexion. Get ready for your healthiest, most-radiant skin ever.

What else you need to know:
This formula's naturally effective complex of ingredients delivers a bevy of benefits. Scrubbing exfoliants lift dead skin cells from surface while papaya, pumpkin, and pineapple enzymes reduce pore size, stimulate circulation, and improve oxygen flow.
Size 0.33 oz/10 mL · ITEM 2021046
exclusive· limited edition· buzzworthy· online only
$16.00

So good!...Best stuff...Good spot treatment for small zits....I have stubborn acne flairups once a month that get huge and stay for over a week and with this twice a day on clean skin it keeps my blemish small and it goes away in 2 days!!
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry
✔ Sensitive

What it is:
An acne treatment gel with a proprietary skin-recovery complex to clear breakouts quickly and promote balanced, smooth skin with no redness, dark spots, or scarring.

Solutions for:
- Acne and blemishes
- Pores
- Redness

If you want to know more…
This formula gently and effectively treats visible acne overnight using a skin-recovery complex that blends salicylic acid, vitamin B3, azelaic acid, caffeine, and other complexion clearers. The formula helps fight redness and unclog pores while calming and soothing post-breakout skin. The result is a clarified, glowing complexion free of redness, dark spots, and hyperpigmentation.

What it is formulated WITHOUT:
- Parabens
- Phthalates

What else you need to know:
This product is dermatologist tested, hypoallergenic, vegan, and fragrance-free.
Size 2.3 oz · ITEM 1817972
exclusive· limited edition· buzzworthy· online only
$48.00

Love this!...holy grail...Would highly recommend to those with any acne...It's not a miracle product, but it makes new acne and old acne smaller and less noticeable while decreasing the lifespan of the pimple.
What it is:
A 10 percent aromatic sulfur mask that dries quickly and clears up acne blemishes.

What it is formulated to do:
This deep pore penetrating, therapeutic formulation absorbs excess surface skin oils, exfoliates dead skin cells, and leaves complexion feeling healthy and refreshed. It clarifies and helps prevent the development of new blemishes and blackheads while allowing skin to heal. Witch hazel and kaolin help purify, and botanicals help calm and soothe acne-prone skin.

What it is formulated WITHOUT:
- Parabens

What else you need to know:
This product is dermatologist tested and approved, allergy tested, hypoallergenic, non-irritating, noncomedogenic, and cruelty-free. It does not contain dye.
Size 0.5 oz/ 15 ml · ITEM 1989276
exclusive· limited edition· buzzworthy· online only
$18.00

AMAZING !...I love it....I have sensitive, acne prone skin....It doesnt sting and good acne treatment for sensitive skin
Which skin type is it good for?
✔ Oily
✔ Combination

What it is:
A spot treatment that targets problem areas on contact to help clear blemishes.

Solutions for:
- Oiliness
- Acne and blemishes

If you want to know more…
Formulated for acne prone or oily skin, this treatment contains two percent salicylic acid to penetrates into pores and reduce acne breakouts. salicylic acid has antibacterial properties to suppress acne-causing bacteria and diminish breakouts. Frankincense helps to reduce oiliness, and ginger root extract soothes and absorbs excess oil for visibly calmer skin.

What else you need to know:
This product is tested under dermatologist supervision. It was inspired by the original Blue Astringent Herbal Lotion, which was formulated in 1964.

Kiehl’s is inspired by its rich heritage as an old-world apothecary, applying over 165 years’ worth of cosmetic, pharmaceutical, herbal, and medicinal knowledge into the formulations. They utilize the finest natural ingredients and incorporate advanced scientific technologies to ensure the highest quality and most efficacious formulas without compromise. They are protective of the environment as they maximize the use of renewable, sustainable, and biodegradable ingredients. Kiehl’s proudly stands behind the quality, efficacy, and safety of each of their products.
Size 0.68 oz/ 20 mL · ITEM 1989318
exclusive· limited edition· buzzworthy· online only
$28.00

Love it!...Thank you!...Pretty reliable acne treatment...It's so nice not having to get a q tip and dip it in and try and get an equal amount so it don't end up with a bunch of dried product I can't use at the end of the bottle that's just wasted.
Which skin type is it good for?
✔ Oily
✔ Combination

What it is:
A spot treatment that targets problem areas on contact to help clear blemishes.

Solutions for:
- Oiliness
- Acne and blemishes

If you want to know more…
Breakout Control Targeted Acne Spot Treatment effectively targets acne and blemishes at the source. Salicylic acid refines skin texture and possesses anti-bacterial properties to suppress acne-causing bacteria, oil-absorbing ginger root extract delivers gingerols to soothe skin, and frankincense helps reduce sebum production.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
This product was inspired by the original Blue Astringent Herbal Lotion formulated in 1964, and is tested under dermatologist supervision. As part of your acne-free skincare routine, start using the Blue Herbal Gel Cleanser, followed by the Blue Astringent Herbal Lotion and Blue Herbal Moisturizer.

Kiehl’s is inspired by its rich heritage as an old-world apothecary, applying over 165 years’ worth of cosmetic, pharmaceutical, herbal, and medicinal knowledge into the formulations. They utilize the finest natural ingredients and incorporate advanced scientific technologies to ensure the highest quality and most efficacious formulas without compromise. They are protective of the environment as they maximize the use of renewable, sustainable, and biodegradable ingredients. Kiehl’s proudly stands behind the quality, efficacy, and safety of each of their products.
ITEM 1778364
exclusive· limited edition· buzzworthy· online only
$22.00

amazing !...I was amazed!...This product works fantastically for the occasional zit....I put it on yesterday night at 9PM and today I woke up at 7AM and it felt dried out and was so much smaller and no pain anymore!
What it is:
A bestselling blemish banisher now in individually wrapped, pre-treated swabs.

What it is formulated to do:
This powerful pink acne treatment is formulated with 10 percent Sulfur—the highest level allowed to effectively fight acne—to help clear skin of blemishes and acne-causing bacteria. It also contains AHAs to reduce the appearance of enlarged pores and help control sebum production. This acne treatment also prevents future breakouts, resulting in a clearer complexion.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
"Do you have a pimple you can feel but can't see? Use EradiKate on the area immediately to help prevent it from surfacing."—Kate Somerville, Founder
Size 0.5 oz/ 15 mL · ITEM 1933100
exclusive· limited edition· buzzworthy· online only
$22.00

It Works...Love it!...I'm not sure what it is about this product, but I was given an acne prescription by my actual doctor to help control hormonal acne as well as cystic acne and that acne prescription never worked as good at this product does....I've had awful acne for about 5 years and I've a lot of scarring and I've tried every product and this is the only thing that has worked for me.
Which skin type is it good for?
✔ Oily
✔ Combination

What it is:
A maximum strength two percent salicylic acid gel formula that reduces blemish size and redness in as little as four hours.

Solutions for:
- Acne and blemishes
- Oiliness
- Pores

If you want to know more…
This maximum strength formula contains salicylic acid to exfoliate, clear pores, and smooth skin. Inspired by pine and thyme extracts, a patented complex fights irritants while preserving skin’s healthy balance. The clear gel formula works well under makeup without pilling or peeling to treat blemishes while concealing.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
The cooling gel soothes skin on contact while going to work immediately to treat blemishes. Apply Rapid Relief Acne Spot Treatment when a blemish is emerging for ultimate control over acne.

This product is an Allure Best of Beauty award winner.

Research results:
In a Murad sponsored study:
- 97% agree blemish appearance improved after just 1 day
Size 5 oz/ 150 ml · ITEM 1989292
exclusive· limited edition· buzzworthy· online only
$22.00

AMAZING this helps with breakeouts, still doesn't dries your skin!
Which skin type is it good for?
✔ Oily
✔ Combination

What it is:
A high foaming acne cleanser that helps purify pores, removing traces of dirt and oil.

Solutions for:
- Oiliness
- Acne and blemishes

If you want to know more…
Inspired by the iconic Blue Astringent Herbal Lotion formulated in 1964, this oil-fighting cleanser is formulated to help clear blemishes, pimples, blackheads, and whiteheads, and prevent new ones from forming. It contains salicylic acid to penetrate deep into pores.

What else you need to know:
This product is tested under dermatologist supervision.

Kiehl’s is inspired by its rich heritage as an old-world apothecary, applying over 165 years’ worth of cosmetic, pharmaceutical, herbal, and medicinal knowledge into the formulations. They utilize the finest natural ingredients and incorporate advanced scientific technologies to ensure the highest quality and most efficacious formulas without compromise. They are protective of the environment as they maximize the use of renewable, sustainable, and biodegradable ingredients. Kiehl’s proudly stands behind the quality, efficacy, and safety of each of their products.
Size 1.7 oz/ 50 g · ITEM 1901230
exclusive· limited edition· buzzworthy· online only
$59.00

Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination

What it is:
A skincare mask designed to visibly clear the complexion.

Solutions for:
- Pores
- Acne and blemishes
- Oiliness

If you want to know more…
SEXY SKIN FOR EVERYONE! NEW SIZE! NEW PRICE!

The SUPERMUD® Clearing Treatment was developed to address common skin concerns, which include blemishes, redness, scars, razor bumps, and in-grown hair. The potent mud formula supports skin’s natural oil balance, while a proprietary blend of six acids (glycolic acid, salicylic acid, lactic acid, mandelic acid, pyruvic acid, and tartaric acid) works to help minimize pores and create clearer skin. Activated-X charcoal lifts away dirt and other skin congestions, resulting in a refined, healthy-looking complexion.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
SUPERMUD is now offered in a 50 g jar—which is 45 percent more for the same price.

This product is an Allure Reader’s Choice award winner.

Research results:
In a consumer study on a number of participants, after 1 day:
- 94% felt their skin looked renewed
- 91% saw an improvement in skin clarity
- 94% felt the product gently cleared their skin

After 3 uses over 7 days:
- 98% reported their skin looked renewed
- 97% saw an improvement in skin clarity
- 97% felt the mask gently cleared their skin
Size 1 oz/ 30 mL · ITEM 1418581
exclusive· limited edition· buzzworthy· online only
$105.00

A WOW!...Solid ....I got a facial at Sephora with good geans and the UFO face oil mixed together and noticed a huge difference in my skin a few hours latter I suffered from redness on my check bones and dark spots from pass acne theses two products made my skin so clear and bright I was amazed the redness had completely gone away my skin looked soft and smooth the dark spots had faded and my skin had such a clear Complexion even my pores had tightened up I'm in love thanks Sunday Riley for makeing me feel beau...My skin was greasy and broke out a lot BUT give it time and your skin will adjust.....after using it consistently for a few weeks I can't believe the changes in my pores and blackheads.....it reminds me of retinol...in the beginning or if you go over board to soon your skin will react negatively but just keep using it.....give it at least a month of consistent use....
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry

What it is:
A clarifying, line smoothing lactic acid treatment.

Solutions for:
- Dullness and uneven texture
- Dark spots
- Fine lines and wrinkles

If you want to know more…
Good Genes All-In-One Lactic Acid Treatment is formulated with high potency, purified grade lactic acid that immediately exfoliates dull, pore-clogging dead skin cells, revealing smoother, fresher, younger-looking skin. Fine lines appear visually plumped while the skin looks more radiant. With continued use, the appearance of stubborn hyperpigmentation and the visible signs of aging are reduced for a healthier-looking complexion. Perfect for all skin types and all ages, this treatment is enhanced with licorice for brightening, Good Genes clarifies, smooths, and retexturizes for instant radiance.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
Backstage at NY Fashion Week, Sunday Riley combines two pumps of Good Genes and one pump of Ceramic Slip Clay Cleanser for a "flash facial." Leave on for one to 10 minutes for an immediately radiant, deep detox facial. This product is cruelty-free.

"As with any AHA, use a sunscreen to prevent sun sensitivity."—Sunday Riley

Research results:
Clinically tested and proven to significantly improve the appearance of lines and wrinkles in 3 minutes. Results obtained via profilometry analysis:
- 100% of women said their skin looked and felt significantly smoother and more radiant, with visibly reduced lines and wrinkles after application
- 100% of women said this was the most effective skin-plumping product they have ever used and would definitely recommend this product to a friend
Size 1.7 oz/ 50 mL · ITEM 1463801
exclusive· limited edition· buzzworthy· online only
$59.00

Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry

What it is:
A professional-quality facial in a jar that softens and brightens in as little as 10 minutes.

Solutions for:
- Fine lines and wrinkles
- Dullness and uneven texture

If you want to know more…
SEXY SKIN FOR EVERYONE! NEW SIZE! NEW PRICE!

The YOUTHMUD™ Tinglexfoliate Treatment moisturizes, exfoliates, and lifts away impurities without disturbing skin’s essential oils. Antiaging ingredients brighten and smooth while delivering a tighter, more youthful appearance with visibly minimized pores.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

Research results:
In a consumer study, after 1 day:
- 97% agreed skin looked and felt smoother
- 91% reported brighter skin
- 94% experienced gentle surface exfoliation

After 3 uses, over 7 days:
- 100% agreed dull skin appeared brighter
- 97% reported gentle surface exfoliation