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Microbiome Skincare Products

Sephora customers often prefer the following products when searching for Microbiome Skincare Products.

Discover the power of microbiome skincare with our curated selection of unique skin care products. Harnessing the science of your skin's natural ecosystem, these innovative formulas work harmoniously with your skin's microbiome to promote a healthier, more balanced complexion. From cleansers and serums to moisturizers and masks, our collection offers a range of options to suit every skincare routine. Explore the transformative benefits of microbiome skincare and unlock a radiant, glowing complexion that is as unique as you are.

ClarinsHydrating Toner Lotion with Aloe Vera

ITEM: 2431443

Size: 6.7 oz / 200 ml

22 Reviews

$49.00

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Love this product!! Makes my skin feel so soft and smooth while giving it a hydrated look...It's out of place with the rest my skincare products, but it works for me! I'm on my third bottle.

What it is: A refreshing, colorant- and alcohol-free face toner that hydrates, visibly balances, and softens normal and dry skin types.

Skin Type: Normal and Dry

Skincare Concerns: Dryness

Formulation: Cream

Highlighted Ingredients:
- Chlorella Extract, Kelp Extract, and Saffron Flower Polyphenols: Protect skin and support its natural microbiome.
- Organic Fig Extract: Hydrates and softens.
- Aloe Vera Extract: Hydrates.

Ingredient Callouts: Free of parabens and sulfates SLS & SLES. It also comes in recyclable packaging.

What Else You Need to Know: Everyday stressors such as harsh cleansers, pollution, temperature swings, humidity, and UV rays can disturb the healthy levels

$79.00

What it is: A gentle, fragrance-free mask with mild AHAs and microbiome-balancing prebiotics that exfoliates and revives dull, dry skin and supports a healthy skin barrier.

Skin Type: Dry

Skincare Concerns: Dryness, Redness, and Dullness

Formulation: Mask

Highlighted Ingredients:
- Self-Neutralizing AHA Blend: Dissolves the appearance of dullness and supports cell turnover.
- Sugar Prebiotic: Helps restore the microbiome balance and maintain skin’s natural defense mechanisms.
- Sugar Carbohydrate Complex: Supports ceramides and proteins to enhance barrier function and provide intense, long-lasting hydration.

Ingredient Callouts: This product is vegan, gluten-free, cruelty-free.

$73.00

It’s so lightweight that I questioned it’s effectiveness at first, but it’s really a hydrating product. I LOVE that it’s intended to help with the skin’s microbiome. ...I like this product! The moisturizer is very nourishing and I like how there are probiotics in it for a healthier skin microbiome.

What it is: A lightweight gel moisturizer that rescues skin from redness, congestion, irritation, and sensitivity with live probiotic cultures that get your skin’s microbiome back in balance.

$119.00

What it is: A cushiony cleanser that delicately dissolves visible build up and polishes without irritation.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Pores, Dryness, and Dullness

Formulation: Cream

Highlighted Ingredients:
- Rice Powder: An ultrafine exfoliant with soothing properties to buff away visible dead skin.
- Wild Harvested Nordic Pine: A natural astringent that helps support natural oils and eliminate the look of impurities.
- Glycolipid Biosurfactant: A non-stripping surfactant that cleanses and supports the microbiome.

Ingredient Callouts: This product is vegan, gluten-free, and cruelty-free.

What Else You Need to Know: This cleanser is ma

$67.00

I was hoping for a spray on product that adds moisture, as I have super dry skin in the winter, but the spray doesn’t spray much product onto the skin. ...It seems to lock in my skincare, giving my face that glowing, hydrated look throughout the day. ...Nice but other products better for cost

What it is: A visibly rebalancing, three-in-one barrier spray to hydrate, soothe, and improve the look of skin tone and texture while supporting skin’s overall health.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Dryness, and Redness

Formulation: Spray

Highlighted Ingredients:
- Fermented Birch Sap: Hydrates and protects the microbiome for visibly calmer, less reactive skin.
- Glacial Water: Rehydrates, visibly rebalances, and cares for skin.
- Squalane: Leaves skin soft and smooth by supporting its barrier.

Ingredient Callouts: This product is vegan, gluten-free, and cruelty-free.

What Else You Need to Know: A microbiome su

$187.00

What it is: A fragrance-free moisturizer with moisture-retentive polysaccharides and hyaluronic acid that cocoons, fortifies, and defends reactive, stressed skin.

Skin Type: Dry

Skincare Concerns: Fine Lines and Wrinkles, Dryness, and Redness

Formulation: Cream

Highlighted Ingredients:
- Micro-algae Peptides: Help shield against sensitizers and protect sensitive skin from overreacting.
- Mondo Root: Helps support the microbiome and the skin’s natural immune defenses.
- Rose of Jericho: Supports moisture levels and nourishes the skin barrier.

Ingredient Callouts: This product is vegan, gluten-free, cruelty-free, and comes in recyclable packaging.

$99.00

use this product at night after the cleanse step in my skincare routine. ...Violette_FR positions C’est La Cream as a prebiotic-based protective barrier cream that supports the skin's microbiome, defends against water loss, and smooths fine lines.

What it is: A multifaceted moisturizer/nourishing barrier shield that locks in moisture, protects against pollution, and restores skin’s supple feel and visible glow.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Dryness, Uneven Texture, and Loss of Firmness and Elasticity

Formulation: Cream

Highlighted Ingredients:
- French Marshmallow Root: Protects against skin-damaging environmental aggressors.
- Dried Japanese Getto Plant Leaves: Support cohesiveness of skin-barrier cells for a glowing complexion.
- Beet Sugars: Nourish the good bacteria in skin’s microbiome for added protection.

Ingredient Callouts: This product is vegan, gluten-free, and cruelty-free.

CLINIQUERedness Solutions Daily Relief Cream with Microbiome Technology

Size: 1.7 oz/ 50 mL·ITEM: 1066729

594 Reviews

$86.00

I have tried so many different skincare products and this one works the best! The redness on my face disappear!...my skin is super sensitive and easily irritated. ive used a lot of skincare product, expensive ones and drugstore products but this is by far my favorite!

What it is: An extra-gentle, oil-free moisturizing cream that instantly calms skin with visible redness—even skin with rosacea.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Redness

Formulation: Cream

Highlighted Ingredients:
- Probiotic (Lactobacillus): Helps strengthen skin’s natural barrier and restore balance to its microbiome, visibly calming irritation.

Ingredient Callouts: Free of sulfates SLS and SLES, parabens, phthalates, and mineral oil.

$95.00

It works well on its own or layered with other products, making it a versatile staple for any skincare collection....Suitable for all skin types, this product fits seamlessly into your daily routine and, thanks to its elegant and functional packaging, becomes an essential addition to any vanity.

What it is: A visibly rebalancing, three-in-one barrier spray to hydrate, soothe, and improve the look of skin tone and texture while supporting skin’s overall health.


Skin Type: Normal, Dry, Combination, and Oily


Skincare Concerns: Fine Lines and Wrinkles, Dryness, and Redness


Formulation: Spray


Highlighted Ingredients:
- Fermented Birch Sap: Hydrates and protects the microbiome for visibly calmer, less reactive skin.

- Glacial Water: Rehydrates, visibly rebalances, and cares for skin.

- Squalane: Leaves skin soft and smooth by supporting its barrier.

$119.00

I think this product would be a great one to start with if you are interested in trying the brand for the first time as it is so easy to incorporate into your skincare routine. ...Adding this product into my skincare routine really helped even out those areas without aggravating my t-zone.

What it is: An ultra-nourishing moisturizer for dry skin that supports cell turnover, visibly diminishes fine lines and wrinkles, and smooths the look of uneven texture.

Skin Type: Normal and Dry

Skincare Concerns: Fine Lines and Wrinkles, Dryness, and Uneven Texture

Highlighted Ingredients:
- BioReplenish Complex™: Proven combination of hydrating lipids to enhance skin's natural resilience.
- Chlorella Algae Complex: A powerful prebiotic that helps rebalance the skin’s natural microbiome.
- Hyaluronic Acid and Aloe Vera: Lock in hydration to enhance the skin’s moisture content.

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“This face mask is hands down one of my favorite face masks that I've tried”
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“Holy grail of all skincare. If I had to eliminate all of my skincare but one, I would keep this”
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