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Sephora customers often prefer the following products when searching for Peptides Creams.

Browse the top-ranked list of Peptides Creams below along with associated reviews and opinions.

Size 1.7 oz/ 50mL · ITEM 2238111
exclusive· limited edition· buzzworthy· online only
$55.00

love the scent...It really works!!...I HIGHLY recommend: )...I could really see a difference in my skin after using this product for a week.
What it is: An oil-free, celery-powered moisturizer that purifies and helps improve hydration retention for poreless, healthier-looking skin.

Skin Type: Oily

Skincare Concerns: Fine Lines and Wrinkles, Pores, and Oiliness

Formulation: Cream

Highlighted Ingredients:
- Celery Seed Extract: Helps smoot, blur, and minimize the appearance of pores.
- Hyaluronic Acid: Replenishes and retains moisture.
- Peptides: Hydrates for visibly plumper skin and minimizes the appearance of fine lines and wrinkles.

Ingredient Callouts: This product is vegan, cruelty-free, and gluten-free, and comes in recyclable packaging.

What Else You Need to Know: Detox you don’t have to drink. Gold medal gymnast Nastia Liukin was ahead of the trend and swore by celery juice since her training years and she wanted its effects from her internal well-being to translate to her skin. Little did she know, she discovered a pore hero.

Clean at Sephora
Clean at Sephora is formulated without a list of over 50 ingredients, including sulfates (SLS and SLES), parabens, phthalates, and more. For the full list, check out the Ingredients tab.
Size 0.5 oz/ 15 mL · ITEM 1930791
exclusive· limited edition· buzzworthy· online only
$35.00

Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry
✔ Sensitive

What it is:
A superfood eye cream packed with antioxidants and tripeptide 5.

Solutions for:
- Fine lines and wrinkles
- Dryness
- Loss of firmness and elasticity

If you want to know more…
Introduce your eyes to the power of superfoods and science. This Superfood Eye Cream delivers vital nutrients with a proprietary superfood blend, aloe vera, ultra-emollient sunflower oil, and an army of reparative vitamins. Crosslinked hyaluronic acid visibly plumps and locks in your skin's natural moisture, while tripeptide 5 supports natural collagen production. Use it daily to help condition, firm, and brighten the appearance of skin around the delicate eye area.

What else you need to know:
This 100 percent vegan eye cream is perfect for all skin types, never tested on animals, and free of parabens, sulfates, and dimethicone. Formulated, filled, and packaged in California, Youth To The People is a family owned company that works in small batches, ensuring you’re getting the freshest and most effective product possible. All extracts are cold pressed and sourced in the U.S.

Clean at Sephora is formulated without a list of over 50 ingredients, including sulfates (SLS and SLES), parabens, phthalates, and more. For the full list, check out the Ingredients tab.
Size 1.7 oz/ 50 mL · ITEM 1981679
exclusive· limited edition· buzzworthy· online only
$195.00

What it is: A rich, peptide-powered moisturizing cream that delivers intense hydration and targets signs of aging for supple, youthful-looking skin.

Skin Type: Dry

Skincare Concerns: Dryness, Fine Lines and Wrinkles, and Loss of Firmness and Elasticity

Formulation: Lotion

Highlighted Ingredients:
- Red Maple Bark: Hydrates and helps reduce the look of premature aging.
- Dual Weight Hyaluronic Acid: Creates a plumping effect for intense hydration.
- Sugar Carbohydrate Complex: Encourages the production of skin’s natural moisturizers.

Ingredient Callouts: This product is vegan, cruelty-free, and comes in recyclable packaging.

What Else You Need to Know: Tata Harper is a real skincare company. They do it all themselves with their own chemists at their own farm. No synthetics. No outsourcing. No shortcuts. 100 percent natural. No toxins, fillers, artificials, synthetics, GMOs. Smells like green beauty. This formula smells like the roots, stems, and absolute essence of every single natural ingredient in their green bottle.

Clean at Sephora
Clean at Sephora is formulated without a list of over 50 ingredients, including sulfates (SLS and SLES), parabens, phthalates, and more. For the full list, check out the Ingredients tab.
Size 1.7 oz · ITEM 1851054
exclusive· limited edition· buzzworthy· online only
$175.00

Which skin type is it good for?
✔ Normal
✔ Combination
✔ Dry

What it is:
A lightweight cream with advanced ceramides to deeply hydrate and a triple peptide blend to visibly smooth the appearance of lines and wrinkles for more youthful-looking skin.

Solutions for:
- Fine lines and wrinkles
- Dryness

If you want to know more…
This powerful antiaging cream helps visibly smooth the appearance of fine lines, wrinkles, and expression lines. Deluxe natural seed oils—including jojoba, babassu, sativa, and macadamia—instantly soften, revive, and moisturize fatigued, dry skin. Super antioxidants and vitamin C help firm and brighten, while the luxurious, light-as-air formula quickly absorbs into skin to instantly relieve dryness.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
The KateCeuticals Collection is the gold standard in sophisticated antiaging skin care. What sets KateCeuticals apart is a triple-reach technology that reaches three depths of skin structure, top to bottom, for dynamic action on all levels. KateCeuticals is infused with a proprietary blend of five premium ingredients working synergistically to create the ultimate antiaging cocktail: concentrated bioactives at the recommended clinical percentage for maximum efficacy and unparalleled results. Kate Somerville has been certified cruelty-free by PETA, solidifying the brand’s commitment to never test their products or ingredients on animals.
Size 1.7 oz/ 50 mL · ITEM 2202521
exclusive· limited edition· buzzworthy· online only
$52.00

What it is: A natural peptide sleeping cream to help you fake a good night's sleep, transforming skin overnight for a firmer, hydrated, younger appearance.

Skin Type: Dry

Skincare Concerns: Fine Lines and Wrinkles, Dullness and Uneven Texture, and Dryness

Formulation: Cream

Highlighted Ingredients:
- Flaxseed Peptide: Energizes and lifts skin’s appearance, reducing the look of fine lines and wrinkles.
- Celery Extract: Rich in vitamins A and C, powerful antioxidants that help fight against photoaging and improve the look of skin health.
- Apple Extract: Natural saccharide complex that helps pull in moisture and keep skin hydrated.

Ingredient Callouts: This product is vegan, cruelty-free, and gluten-free, and comes in recyclable packaging.

What Else You Need to Know: This multi-targeted overnight sleeping cream is no rinse, just results. Its rich creamy texture with a non-greasy feel absorbs quickly into the skin to rebound, strengthen, and hydrate the skin to maximize beauty sleep and put your best face forward.

Clincal Results: Based on a 7-day consumer perception study of 45 women in 2019, ranging in age from 25 to 50:
- 100% agreed their skin looked healthy
- 100% agreed they would recommend this sleeping cream to anyone
- 98% agreed their skin looked energized and luminous
- 96% agreed it was the best overnight cream they had ever used
- 91% agreed fine lines and wrinkles were less visible

Clean at Sephora
When you spot our Clean seal, you can be sure we’ve checked that this brand’s product is made without the ingredients you told us you’d most like to avoid. 

Clean at Sephora™ is formulated without: 
Sulfates SLS and SLES, parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, triclosan, triclocarban. All skincare, hair, and makeup brands with the Clean Seal have less than one percent of synthetic fragrances.
Size 0.51 oz/ 15 mL · ITEM 2168383
exclusive· limited edition· buzzworthy· online only
$40.00

What it is: A peptide-powered eye cream that targets fine lines and wrinkles while hydrating for a youthful, well-rested appearance.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Pores, and Loss of Firmness and Elasticity

Formulation: Cream

Highlighted Ingredients:
- Peptide Blend (Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-1, and Palmitoyl Tetrapeptide-7): Supports natural cell renewal and targets fine lines and wrinkles for smooth, visibly plump, and youthful skin.
- Organic Gingko Biloba Extract: Rich in antioxidants to help protect against environmental stressors, signs of aging, and inflammation.
- Green Tea Extract: Packed with antioxidants that repair and protect skin from signs of aging.

Ingredient Callouts: This product is vegan, cruelty-free, and gluten-free.

What Else You Need to Know: A trio of age-defying peptides help support natural cell renewal for smooth and visibly plump skin. In addition, organic, antioxidant-packed gingko biloba, avocado oil, almond oil, and sesame oil extracts protect skin against environmental stressors and help diminish the signs of premature aging.

Clean at Sephora
Clean at Sephora is formulated without a list of over 50 ingredients, including sulfates (SLS and SLES), parabens, phthalates, and more. For the full list, check out the Ingredients tab.
Size 1.08 oz/ 32 mL · ITEM 1868140
COLOR: Fair [ 11 more colors ]
exclusive· limited edition· buzzworthy· online only
$39.00

What it is: A bestselling, award-winning, color-correcting, full-coverage cream with SPF 50+ physical sunscreen.

Skin Type: Normal, Dry, Combination, and Oily

Formulation: Full Cream

Highlighted Ingredients:
- Collagen: Supports skin elasticity for a youthful, smooth appearance.
- Peptides: Help reduce the appearance of wrinkles and support natural collagen for the look of smoother, firmer skin.
- Hyaluronic Acid: Locks in moisture, supports skin elasticity, and diminishes the look of fine lines and wrinkles.

Ingredient Callouts: Free of parabens and phthalates.

What Else You Need to Know: It's your full-coverage foundation, SPF 50+ physical sunscreen, brightening color corrector, hydrating serum, poreless-finish primer, dark spot concealer, and moisturizing day cream all in one! Diffuses the appearance of dark spots, redness, hyperpigmentation, and other skin imperfections.

Clinical Results: Based on a clinical study, immediately after use:
- 100% of participants reported increased skin hydration

After 10 days:
- 96% of participants reported softer, smoother skin
- 85% of participants reported an improvement in the appearance of wrinkles
- 77% of participants reported pores appeared smaller
Size 1.69 oz/ 50 mL · ITEM 2086304
exclusive· limited edition· buzzworthy· online only
$39.00

Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry
✔ Sensitive

What it is:
An anti-aging glacier water cream that delivers mineral-rich moisture while protecting skin from free radicals; a fusion of ferments, amino acids, and plant extracts help calm skin while boosting vitality and suppleness.

Solutions for:
- Dryness
- Dullness and uneven texture
- Pores

If you want to know more…
A patented concentration of the CHA 7 es complex™ targets seven signs of early aging by improving your skin's moisture level, texture, and tone. Alaska glacier water protects skin from free radicals while promoting optimal absorption of moisture. XPERTMOIST's fusion of ferments and amino acids shield skin from dehydration while improving skin vitality. Iceland moss extract calms and reduces inflammation while promoting hydration.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
"The key to Saturday Skin is the Cha-7 es complex, an exclusive peptide formula that promotes skin's natural regeneration process. Rooted in science and derived from natural ingredients, the cutting-edge complex supports natural collagen and elasticity while reducing melanin production for a flawless, stress-free complexion. The complete collection helps you hit pause on aging and embrace your bare beauty. Free of added color and fragrance, the no-fuss, effortless regimen balances and revitalizes all skin types, leaving you free to soak up your Saturdays and keep on glowing all week long.
Size 1.69 oz/ 50 mL · ITEM 2014298
exclusive· limited edition· buzzworthy· online only
$49.00

Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry
✔ Sensitive

What it is:
A lightweight moisturizer that protects and softens for supple skin.

Solutions for:
- Dryness
- Loss of firmness and elasticity
- Fine lines and wrinkles

If you want to know more…
Featherweight Daily Moisturizing Cream features the patented peptide complex with nutrient fruit extracts that improve the look of skin's moisture level, texture, and tone. Avocado protein extracts help strengthen the appearance of skin barrier, while antioxidants like peach extract promote maximum hydration and promote a supple look and feel of skin.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
The key to Saturday Skin is the Cha-7 es Complex™, an exclusive peptide formula that supports the skin's natural regeneration process. Rooted in science and derived from natural ingredients, the complex supports collagen and elasticity while reducing melanin production for a flawless complexion.

This product is cruelty-free and formulated without added color and fragrance.
Size 0.5 oz/ 15 mL · ITEM 1774819
exclusive· limited edition· buzzworthy· online only
$27.50

Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry
✔ Sensitive

What it is:
An instant brightening and hydrating eye cream that features a blend of peptides to help combat the visible effects of your busy life.

Solutions for:
- Dryness
- Puffiness

If you want to know more…
This lightweight eye cream provides a rush of hydration and instant brightening so you look and feel refreshed, wide awake, and ready for anything in as little as three seconds. Its cool touch and de-puffing tip help keep eyes looking fresh while smoothing the way for makeup. Plus, its peptides help support natural collagen reserves that can be threatened by stress, fatigue, and lack of sleep—the tell-tale signs of your busy life.

What it is formulated WITHOUT:
- Parabens

What else you need to know:
This product is allergy and ophthalmologist tested, and free of oil and fragrance.

This product is an Allure Best of Beauty award winner.
Size 0.37 oz · ITEM 1868231
exclusive· limited edition· buzzworthy· online only
$32.00

Skin type:
✔ Normal
✔ Dry
✔ Combination
✔ Oily

What it is:
A revolutionary skin care cream that completely cancels out redness, color corrects, and delivers full coverage in one step.

What it does:
Bye Bye Redness™ is a color-infused skin care product that works as a skin-calming cream and completely cancels redness from view—all while delivering long-wearing, color-correcting full coverage. Rich in antiaging ingredients—including colloidal oatmeal, hydrolyzed collagen, peptides, aloe and avocado—it camouflages any red-toned skin discolorations including rosacea, broken capillaries, blemishes, skin irritations, sun damage, scars, age spots, and more. Perfect for all skin types, this soothing, cutting-edge, super-blendable cream provides perfect coverage that never creases or cracks and makes your skin appear supple, even, and youthfully radiant all day long. One universal shade works for all skin tones.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
This product was developed with plastic surgeons and dermatologists. It is clinically tested, talc-free, bismuth-free, and cruelty-free.
Size 0.5 oz · ITEM 1868124
exclusive· limited edition· buzzworthy· online only
$48.00

What it is: A hydrating under-eye cream designed to reduce the appearance of dark circles, lines, and wrinkles and improve the look of eye bags.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Dark circles, Fine lines and wrinkles, Loss of firmness and elasticity

Formulation: Cream

Highlighted Ingredients:
- Collagen: Supports skin elasticity for a youthful, smooth appearance.
- Cucumber Extract: Has soothing properties and helps reduce the appearance of puffiness.
- Hyaluronic Acid: Locks in moisture, supports the look of skin elasticity, and diminishes the look of fine lines and wrinkles.

Ingredient Callouts: Free of sulfates SLS and SLES, parabens, and phthalates.

What Else You Need to Know: This quick-absorbing, intensely hydrating eye cream is clinically tested to make your entire eye area appear firmer. Its exclusive "dark shadow minimizing" blue tint helps to brighten the look of dark under-eye circles. The formula is also infused with collagen, caffiene, hyaluronic acid, and cucumber extract.

Clinical Results: In an independent clinical study:
- 100% showed a clinically measured increase in skin hydration
- 95% said it smoothed and nourished eye area
- 80% said eye area appeared well-rested and felt immediately revived