Get 4X Points†† on ALL Makeup! Ends 3/4. ††Exclusions/terms apply. Use code MAKEUPMATH ▸

Sign Infor FREE Shipping

Serums With Peptides

Sephora customers often prefer the following products when searching for Serums With Peptides.

Discover the power of peptides with this collection of serums. Peptides are small chains of amino acids that play a crucial role in maintaining the health and appearance of your skin. These potent ingredients have been hailed for their ability to target specific concerns, such as fine lines, wrinkles, and loss of elasticity. This range of serums with peptides offers a variety of formulations designed to nourish, hydrate, and rejuvenate your skin. Whether you're looking to boost collagen production, improve skin texture, or enhance overall radiance, this selection of serums with peptides has something for everyone.

Peter Thomas RothPeptide Skinjection Amplified Wrinkle-Fix Serum

ITEM: 2737252

Size: 1 oz

299 Reviews

$90.00

Buy Now

This product uses a combination of peptides to smooth skin and reduce fine lines. [19% peptide complex of amplified matrixyl & argireline] Peptides in skincare are known for stimulating collagen production and restore elasticity. ...The Peptide Skinjection Amplified Wrinkle-Fix Serums impresses me with its refillable design and 19% peptide complex.

What it is: A noninvasive, dual-purpose, and refillable serum with a peptide complex that is clinically shown to improve the look of expression lines.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines, Wrinkles, and Loss of Firmness and Elasticity

Highlighted Ingredients:
- 19% Peptide Complex of Amplified Matrixyl® and Argireline®: Reduces and prevents the look of expression lines.
- 10% Argirelox: Helps prolong the need for next injectable treatment by up to 6 months.†

Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, sulfates SLS & SLES, triclocarba

$85.00

I am absolutely loving the super ingredients in the Peptide Skinjection Serum! The peptides are helping improve my skin barrier immensely and Agireline is my favorite skincare ingredient to keep the wrinkles and fine lines away. ...Peptides are the holy grail for aging skin and I’ve got to say I am in love with Peter Thomas Roth Peptide skinjection!

What it is: A noninvasive, dual-purpose, and refillable serum with a 19% peptide complex that is clinically shown to improve the look of expression lines.
Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Loss of Firmness and Elasticity

Highlighted Ingredients:
- 19% Peptide Complex of Amplified Matrixyl® and Argireline®: Reduce and prevent the look of expression lines.
- 10% Argirelox: Helps prolong the need for next injectable treatment by up to six months.†

Ingredient Callouts: Free of parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, sulfates SLS & SLES, triclocarba

$23.50

This serum contains 7 peptides and 11 individual amino acids. ...Firmer-feeling skin,powered by peptides. With 4 skin-firming peptide technologies in one powerful serum.

What it is: A comprehensive peptide serum to help address common signs of early skin aging, including the look of fine lines and the feel of skin elasticity.                       


Skin Type: Normal, Dry, Combination, and Oily


Skincare Concerns: Fine Lines and Wrinkles, Dryness, and Loss of Firmness and Elasticity


Formulation: Lightweight Serum



$77.00

Soo good serum...I love that it can be used on eyes and has peptides. Mine is in the fridge in the summer because it feels amazing on....Amazing Serum!...However the clean ingredients in the Triple Peptide+ Cactus + Firming Oasis Serum piqued my interest.

What it is: A potent, triple-peptide infused hyaluronic acid eye and face serum that intensely hydrates, visibly plumps and firms to sustain bouncy, youthful skin.

Skin Type: Normal, Dry, Combination, and Oily


Skincare Concerns: Fine Lines/Wrinkles, Dryness, and Loss of Firmness/Elasticity


Formulation: Lightweight Gel


Highlighted Ingredients:

- 4D Hyaluronic Acid: Hydrates, visibly plumps, and revitalizes thirsty skin cells.

- Triple Bio-peptide Blend: Visibly improves look of fine lines and wrinkles.

- Cactus and Rambutan Peel Extracts: Moisture-binding plant extracts help skin hang onto hydration longer.

$30.00

The Rhode Flewy Dewy Gel-Serum is nothing short of extraordinary. Even when skipped, my skin remains soft, hydrated, and radiantly luminous—proof of its lasting efficacy. ...Don’t get negative reviews, this serum absorbs great, perfect for summer instead of heavy cream I’ll definitely repeat!

What it is: A lightweight, quick-absorbing gel serum that hydrates and brightens the look of skin while visibly plumping skin over time.


Skin Type: Normal, Dry, Combination, and Oily


Skincare Concerns: Dullness, Dryness, and Uneven Texture


Formulation: Serum


$90.00

What it is: A visibly plumping and firming serum with exosomes, stem cells, and a GF peptide complex to increase the look of fullness and elasticity.


Skin Type: Normal, Dry, and Combination 


Skincare Concerns: Fine Lines and Wrinkles, Dullness, and Loss of Firmness and Elasticity 


Formulation: Serum


Highlighted Ingredients:

- Plant-Derived Exosomes, Stem Cells, and GF Peptide Complex: Extracted from goji berry, althaea rosea, and n. benthamiana plants.

$48.00

Peptide Glazing Fluid...I’ve purchased more than once and I absolutely love this lightweight hydrating serum!! 🤍☁️✨ I also love the new packaging! Great for sensitive/acne skin also!...A must have serum!...I’m so happy that Rhode is coming to Sephora! The peptide glazing fluid serum is so good as a part of the 3 step kit but also with other toners and cream as well.

What it is: A lightweight, quick-absorbing gel serum that hydrates and brightens the look of skin while visibly plumping over time.


Skin Type: Normal, Dry, Combination, and Oily


Skincare Concerns: Dullness, Dryness, and Uneven Texture


Formulation: Serum


$95.00

I recently had the opportunity to try the Sulwhasoo, Concentrated Ginseng Rejuvenating Serum. So far,!Im loving this serum! The serum itself feels incredibly lightweight m, silky and luxurious....Must have anti aging serum...My skin looks radiant and youthful , my neck feels less saggy and my complexion looks more natural and toned. This anti-aging serum is enriched with ginseng, retinol and peptides that visibly firm skin, improves wrinkles and promotes a more voluminous complexion.

What it is: A visibly firming serum enriched with ginseng and retinol capsules to reduce the look of fine lines and wrinkles in as soon as seven days for skin that feels smoother and rejuvenated.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Uneven Texture, and Loss of Firmness and Elasticity

Highlighted Ingredients:
- Ginseng Actives (a.k.a. Ginsenomics): Help skin feel rejuvenated and strengthened for a healthy, youthful look.
- Ginseng Peptide: Supports visible firmness and elasticity.
- Ginseng Capsules with Retinol: Burst upon application to deliver powerful benefits that target visible signs of aging.

Ingredient Callouts: Free of parabens, formaldehyd

$30.00

VERB Density Peptide Serum boosts hair thickness and scalp health with peptides, biotin, and caffeine. ...This peptide serum really did the job! After applying the peptide shampoo it left my scalp feeling tingling and so clean!

What it is: A lightweight hair serum, with ginseng root extract and niacinamide, that visibly increases hair density and minimizes the appearance of thinning hair.

Hair Texture: Straight, Wavy, Curly, and Coily

Hair Type: Fine, Medium, and Thick

Hair Concerns:
- Thinning

Key Benefits:
- Helps hair appear denser
- Visibly increases hair thickness and fullness
- Reduces visible signs of hair shedding and fallout

Highlighted Ingredients:
- Verb’s Unique Density Complex: Supports hair growth.
- Ginseng Root Extract: Increases the size and depth of hair follicles.
- Niacinamide: Boosts blood circulation for visibly thicker, fuller hair.

$21.20

This isn’t only a vitamin C derivative serum - there’s also peptides and ginseng extract. ...I like this serum! The price point is great for the formula that you’re getting — there’s a stable form of Vitamin C (I’ve had mine for a few weeks and it still hasn’t oxidized which is a good sign) and other antioxidant ingredients like targeted peptides, ergothionine and EGCG.

What it is: A daily antioxidant serum with eight technologies, including vitamin C and ginseng, that protects and visibly brightens dull skin.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine Lines and Wrinkles, Dullness, and Uneven Texture

Formulation: Serum

Highlighted Ingredients:
- Ascorbyl Glucoside: A stabilized form of vitamin C that supports skin’s natural collagen.
- Ginseng Extract: A plant extract that helps protect and soothe skin’s stress response.
- EGCG: Designed to help shield against environmental irritants.

Products related to Serums With Peptides

Eye Creams With Peptides
“[I received this product in exchange for my honest review] My under eyes have always been very sensitive with eye creams”
Moisturizers With Peptides
“I have been really enjoying using the Peter Thomas Roth Peptide 21 Wrinkle Resist product line! Both the serum and moisturizer feel extremely light weight on the skin and are formulated with an amazing Peptide complex”
Peptides Creams
“I have very sensitive skin and since using the product on my neck and arms It has protected my skin from not breaking out with skin rash while being out in the sun. The moisturizing cream is very smooth on my skin and has not stained any of my clothes”
Serums With Ceramides
“Kiehl's Since 1851 Micro-Dose Anti-Aging Retinol Serum with Ceramides and Peptide. Thicker than other serums”
Peptide Eye Serum
“I recently tried the Guerlain Double R Eye Serum, and I'm so glad that I did! This eye serum is designed to reduce wrinkles and puffiness around the eyes”
Peptides Skin Care Products
“It has a Powerful blend of caffeine and highly active peptides that I always look for to make it happen - refreshed eyes”
Sunscreen With Peptides
“I have tried a few sunscreens and this one has been the only one that doesn’t pill on my face”
Eye Serums
“I recently tried the Guerlain Double R Eye Serum, and I'm so glad that I did! This eye serum is designed to reduce wrinkles and puffiness around the eyes”
Pearl Serums
“ONE/SIZE B12 Base Thinner Vitamin Pearl Serum is a hydrating, lightweight serum that blends the power of Vitamin B12 with illuminating pearls for a radiant, healthy glow”
Collagen Serums
“This luxuary collagen activating serum is very nice. It has a faint fragrance that smells great”

Related Content:

Thinning Hair & Hair Loss Products, Pore Minimizing Products, Face Serum & Face Treatments, Best Hair Products For Dry Hair, Best Eyebrow Makeup in 2026, Best Eye Creams of 2024, Best Foundations for Oily Skin in 2024, Best Brow Products For You | Brow Quiz, Best Affordable Makeup in 2026