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Sephora customers often prefer the following products when searching for Pimple Spot Treatments.

Browse the top-ranked list of Pimple Spot Treatments below along with associated reviews and opinions.

Size 0.14 oz/ 4.4 mL · ITEM 1164110
exclusive· limited edition· buzzworthy· online only
$18.00

Love it...Um, Wow...It does actually heal my breakouts, BUT.......It works best as a preventative, so when I feel a bump under the skin and know a blemish is coming on, I treat it immediately and the blemish never actually surfaces!
What it is:
A botanically-based spot treatment for acne blemishes.

What it does:
Botanical willow bark helps provide relief from breakouts effectively and safely, even for the most sensitive skin. This unique anti-irritant calms inflammation while soapberry peel cleans and purifies. A combination of jojoba leaf and vitamins C and E work with other effective ingredients to help reduce redness, control oil, maintain a clear complexion, and combat free radicals.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
This product is ideal for all skin types, including sensitive skin.

Clean at Sephora
When you spot our Clean seal, you can be sure we’ve checked that this brand’s product is made without the ingredients you told us you’d most like to avoid. 

Clean at Sephora™ is formulated without: 
Sulfates SLS and SLES, parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, Triclosan, Triclocarban. All skincare, hair, and makeup brands with the Clean Seal have less than one percent of synthetic fragrances.
Size 0.5 oz/ 15 mL · ITEM 1933100
exclusive· limited edition· buzzworthy· online only
$22.00

SO GOOD....Worth it...I used the smallest dot on each breakout area and it worked like a charm....I am a fan of Murad products, and I wanted to really like this, but to be honest it doesn't work any better than a spot 5 dollar spot treatment from a grocery store.
Which skin type is it good for?
✔ Oily
✔ Combination

What it is:
A maximum strength two percent salicylic acid gel formula that reduces blemish size and redness in as little as four hours.

Solutions for:
- Acne and blemishes
- Oiliness
- Pores

If you want to know more…
This maximum strength formula contains salicylic acid to exfoliate, clear pores, and smooth skin. Inspired by pine and thyme extracts, a patented complex fights irritants while preserving skin’s healthy balance. The clear gel formula works well under makeup without pilling or peeling to treat blemishes while concealing.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
The cooling gel soothes skin on contact while going to work immediately to treat blemishes. Apply Rapid Relief Acne Spot Treatment when a blemish is emerging for ultimate control over acne.

This product is an Allure Best of Beauty award winner.

Research results:
In a Murad sponsored study:
- 97% agree blemish appearance improved after just 1 day
Size 0.33 oz/10 mL · ITEM 2021046
exclusive· limited edition· buzzworthy· online only
$16.00

So good!...Best stuff...I use all over my face since I'm very acne prone, and have noticed a decrease in size of my pimples....It says to apply to a clean face up to 3 times a day, but I only use it twice because I have to leave my make up on... I swear it takes away the biggest/reddest bumps ever!
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry
✔ Sensitive

What it is:
An acne treatment gel with a proprietary skin-recovery complex to clear breakouts quickly and promote balanced, smooth skin with no redness, dark spots, or scarring.

Solutions for:
- Acne and blemishes
- Pores
- Redness

If you want to know more…
This formula gently and effectively treats visible acne overnight using a skin-recovery complex that blends salicylic acid, vitamin B3, azelaic acid, caffeine, and other complexion clearers. The formula helps fight redness and unclog pores while calming and soothing post-breakout skin. The result is a clarified, glowing complexion free of redness, dark spots, and hyperpigmentation.

What it is formulated WITHOUT:
- Parabens
- Phthalates

What else you need to know:
This product is dermatologist tested, hypoallergenic, vegan, and fragrance-free.
Size 0.5 oz/ 15 ml · ITEM 1989276
exclusive· limited edition· buzzworthy· online only
$18.00

AMAZING !...I love it....With one use, any pimple is significantly smaller....This thing works for me: I feel a pimple growing, I put it on, pimple shrinks away.
Which skin type is it good for?
✔ Oily
✔ Combination

What it is:
A spot treatment that targets problem areas on contact to help clear blemishes.

Solutions for:
- Oiliness
- Acne and blemishes

If you want to know more…
Formulated for acne prone or oily skin, this treatment contains two percent salicylic acid to penetrates into pores and reduce acne breakouts. salicylic acid has antibacterial properties to suppress acne-causing bacteria and diminish breakouts. Frankincense helps to reduce oiliness, and ginger root extract soothes and absorbs excess oil for visibly calmer skin.

What else you need to know:
This product is tested under dermatologist supervision. It was inspired by the original Blue Astringent Herbal Lotion, which was formulated in 1964.

Kiehl’s is inspired by its rich heritage as an old-world apothecary, applying over 165 years’ worth of cosmetic, pharmaceutical, herbal, and medicinal knowledge into the formulations. They utilize the finest natural ingredients and incorporate advanced scientific technologies to ensure the highest quality and most efficacious formulas without compromise. They are protective of the environment as they maximize the use of renewable, sustainable, and biodegradable ingredients. Kiehl’s proudly stands behind the quality, efficacy, and safety of each of their products.
Size 2.3 oz · ITEM 1817972
exclusive· limited edition· buzzworthy· online only
$48.00

holy grail...Love this!...After about 2 days, pimple is gone....So, I would not use this as a full face mask again, but I love the spot treatment use of this product.
What it is:
A 10 percent aromatic sulfur mask that dries quickly and clears up acne blemishes.

What it is formulated to do:
This deep pore penetrating, therapeutic formulation absorbs excess surface skin oils, exfoliates dead skin cells, and leaves complexion feeling healthy and refreshed. It clarifies and helps prevent the development of new blemishes and blackheads while allowing skin to heal. Witch hazel and kaolin help purify, and botanicals help calm and soothe acne-prone skin.

What it is formulated WITHOUT:
- Parabens

What else you need to know:
This product is dermatologist tested and approved, allergy tested, hypoallergenic, non-irritating, noncomedogenic, and cruelty-free. It does not contain dye.
Size 0.68 oz/ 20 mL · ITEM 1989318
exclusive· limited edition· buzzworthy· online only
$28.00

Love it!...Thank you!...It's so nice not having to get a q tip and dip it in and try and get an equal amount so it don't end up with a bunch of dried product I can't use at the end of the bottle that's just wasted....I think this spot treatment is underrated: It really works very quickly and effectively to eliminate my occasional breakout.
Which skin type is it good for?
✔ Oily
✔ Combination

What it is:
A spot treatment that targets problem areas on contact to help clear blemishes.

Solutions for:
- Oiliness
- Acne and blemishes

If you want to know more…
Breakout Control Targeted Acne Spot Treatment effectively targets acne and blemishes at the source. Salicylic acid refines skin texture and possesses anti-bacterial properties to suppress acne-causing bacteria, oil-absorbing ginger root extract delivers gingerols to soothe skin, and frankincense helps reduce sebum production.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
This product was inspired by the original Blue Astringent Herbal Lotion formulated in 1964, and is tested under dermatologist supervision. As part of your acne-free skincare routine, start using the Blue Herbal Gel Cleanser, followed by the Blue Astringent Herbal Lotion and Blue Herbal Moisturizer.

Kiehl’s is inspired by its rich heritage as an old-world apothecary, applying over 165 years’ worth of cosmetic, pharmaceutical, herbal, and medicinal knowledge into the formulations. They utilize the finest natural ingredients and incorporate advanced scientific technologies to ensure the highest quality and most efficacious formulas without compromise. They are protective of the environment as they maximize the use of renewable, sustainable, and biodegradable ingredients. Kiehl’s proudly stands behind the quality, efficacy, and safety of each of their products.
Size 1 oz/ 30 mL · ITEM 1592831
exclusive· limited edition· buzzworthy· online only
$27.00

IN LOVE...LOVE IT...It helps dry those pimples right up....I have pcos and my acne is horrible, I have tried antibiotics topical treatment prescribed from my doctor nothing helped my cystic acne, decided to try my sample and noticed a huge difference in the morning, this is amazing I am actually hopefully I can get rid of my acne and have a clear face again like I use to.
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry

What it is:
A daily treatment gel for acne-clearing results equal to a leading topical prescription.

Solutions for:
- Acne and blemishes
- Pores
- Oiliness

If you want to know more…
This ultra-powerful daily treatment gel is powered by Clinique’s four-in-one clearing complex with salicylic acid to start clearing blemishes instantly and help prevent new ones from forming. You can make visibly clearer skin a way of life.

What it is formulated WITHOUT:
- Parabens

What else you need to know:
This product is allergy tested, non-acnegenic, and free of oil and fragrance.

This product is an Allure Best of Beauty award winner.
Size 0.5 oz/ 15 mL · ITEM 1592856
exclusive· limited edition· buzzworthy· online only
$18.00

Love it....WORTH IT...This gel is amazing!...The results are so much better than I expected, and I'm thankful to be able to go without makeup for the first time in months (before I felt self-conscious even answering the door to get a delivery at home without wearing make-up!
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry

What it is:
A daily treatment gel for acne-clearing results equal to a leading topical prescription.

Solutions for:
- Acne and blemishes
- Pores
- Oiliness

If you want to know more…
This ultra-powerful daily treatment gel is powered by Clinique’s four-in-one clearing complex with salicylic acid to start clearing blemishes instantly and help prevent new ones from forming. You can make visibly clearer skin a way of life.

What it is formulated WITHOUT:
- Parabens

What else you need to know:
This product is allergy tested, non-acnegenic, and free of oil and fragrance.

This product is an Allure Best of Beauty award winner.
Size 1 oz/ 30 mL · ITEM 1418581
exclusive· limited edition· buzzworthy· online only
$105.00

A WOW!...I love....My skin is brighter, smoother, softer, and less prone to breakouts....I got a sample with my order and I tried on after my black mask and the results were amazing, the next day everybody gave me complements on my skin I have sensitive skin and I love this product I went back to sephora store and got me a full size, I love this stuff I use it only at night my skin feels great the next morning looks amazing between my clarasonic, the sunday riley face wash and the good genes treatment my skin looks awesome.
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry

What it is:
A clarifying, line smoothing lactic acid treatment.

Solutions for:
- Dullness and uneven texture
- Dark spots
- Fine lines and wrinkles

If you want to know more…
Good Genes All-In-One Lactic Acid Treatment is formulated with high potency, purified grade lactic acid that immediately exfoliates dull, pore-clogging dead skin cells, revealing smoother, fresher, younger-looking skin. Fine lines appear visually plumped while the skin looks more radiant. With continued use, the appearance of stubborn hyperpigmentation and the visible signs of aging are reduced for a healthier-looking complexion. Perfect for all skin types and all ages, this treatment is enhanced with licorice for brightening, Good Genes clarifies, smooths, and retexturizes for instant radiance.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
Backstage at NY Fashion Week, Sunday Riley combines two pumps of Good Genes and one pump of Ceramic Slip Clay Cleanser for a "flash facial." Leave on for one to 10 minutes for an immediately radiant, deep detox facial. This product is cruelty-free.

"As with any AHA, use a sunscreen to prevent sun sensitivity."—Sunday Riley

Research results:
Clinically tested and proven to significantly improve the appearance of lines and wrinkles in 3 minutes. Results obtained via profilometry analysis:
- 100% of women said their skin looked and felt significantly smoother and more radiant, with visibly reduced lines and wrinkles after application
- 100% of women said this was the most effective skin-plumping product they have ever used and would definitely recommend this product to a friend
Size 1 oz · ITEM 1167147
exclusive· limited edition· buzzworthy· online only
$26.00

I win....love it...None of my pimples ever become white and pus filled anymore (that was so gross)....It's very hard not to shake the bottle up and it does take a little practice to not get to much of the pink on a Q-tip, if you do it drips down your face, you don't need a lot but this stuff is GREAT I don't usually give reviews.....if I do its usually to tell people how awful things are so when I do give a good review it's for good reason!!!
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry

What it is:
An effective blemish-fighting acne treatment to minimize pimples, zits, and help prevent future breakouts.

Solutions for:
- Acne/blemishes
- Pores

If you want to know more…
Kate's bestselling EradiKate™ Acne Treatment is specifically formulated with the highest level of sulfur allowed to effectively fight blemishes, reduce acne, and help keep skin free of new breakouts. AHAs are designed to reduce the appearance of enlarged pores while zinc oxide, a natural mineral, provides oil control by absorbing excess sebum. The result is clearer skin that lasts.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
EradiKate Acne Treatment is most effective when applied to affected areas as soon as blemishes or pimples are noticed.

"Do you have a pimple you can feel but can't see? Use EradiKate on the area immediately to help prevent it from surfacing."—Kate Somerville, Founder
Size 1 oz/ 30 mL · ITEM 1164094
exclusive· limited edition· buzzworthy· online only
$35.00

it's ok...In Love...Good for reducing acne but doesn't eliminate...The girl who helped me suggested I use it as an all over treatment (since my cyclic acne is pretty bad) around my period, and I do notice that my skin looks a little better.
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry
✔ Sensitive

What it is:
A highly effective, lightweight daily treatment gel that helps clear congested skin and addresses the cause of future blemishes.

Solutions for:
- Blemishes
- Pores
- Uneven texture

If you want to know more…
This soothing treatment gel is formulated to help absorb excess oil, purify skin, unclog pores, and maintain a clear-looking complexion without irritation.

What else you need to know:
This product is preservative-free for sensitive skin. It’s also artificial fragrance and color-free, gluten-free, ethanol alcohol-free, and dermatologist tested.

Essential to every boscia product is their botanical blend: an effective mix of jojoba leaf and willow herb. Jojoba leaf is a powerful antioxidant that helps to prevent free radical damage caused by pollution, UV rays, and other environmental irritants. Willow herb is a natural skin-calming botanical that helps to alleviate inflammation and redness.

Clean at Sephora
When you spot our Clean seal, you can be sure we’ve checked that this brand’s product is made without the ingredients you told us you’d most like to avoid.

Clean at Sephora™ is formulated without:
Sulfates SLS and SLES, parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, Triclosan, Triclocarban. All skincare, hair, and makeup brands with the Clean Seal have less than one percent of synthetic fragrances.

Clean at Sephora
When you spot our Clean seal, you can be sure we’ve checked that this brand’s product is made without the ingredients you told us you’d most like to avoid.

Clean at Sephora™ is formulated without:
Sulfates SLS and SLES, parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, Triclosan, Triclocarban. All skincare, hair, and makeup brands with the Clean Seal have less than one percent of synthetic fragrances.
Size 1 oz/ 30 mL · ITEM 1572445
exclusive· limited edition· buzzworthy· online only
$56.00

Love it...So nice...No pimples, no extra redness....I'm currently taking medication that is drying me out completely my skin was flaking and everything my normal lotions were soaking right up and I had to keep re-applying constantly especially in the middle of the night I bought this and I apply in the morning before makeup and at night after removing makeup and when I wake up my skin looks radiant and hydrated I also started using the regular argan oil along with this and feels even batter!
Which skin type is it good for?
✔ Combination
✔ Dry
✔ Sensitive

What it is:
A 100 percent natural, emulsifier-free treatment serum that visibly plumps and deeply hydrates.

Solutions for:
- Fine lines and wrinkles
- Loss of firmness and elasticity

If you want to know more…
Josie’s revolutionary anti-aging Pure Argan Milk marries the hydration of skin-balancing purified water with rejuvenating 100% Pure Argan Oil for plumper-looking, nourished skin. This lightweight yet super-intensive hydrating serum penetrates deeply and absorbs quickly to preserve the elasticity and bounce of skin's youthful cushion. The 100% Pure Argan Oil repairs and fortifies with a weightless combination of essential fatty acids, antioxidants, and vitamin E to reveal fresher, healthier, more radiant skin packed with long-lasting moisture. Use under Face Butter and Argan Oil for amplified moisture and glow.

What else you need to know:
This product is vegan, cruelty-free, and formulated without gluten, GMO, synthetic fragrance, and formaldehyde.

Research results:
Allure Beauty Enthusiasts Panel, October 2013 in a 4-week product trial; each participant received a complimentary full-size Pure Argan Milk and used it twice daily; 222 respondents to the 24-hour survey; 196 respondents:
- 85% of women reported their skin was more hydrated and felt hydrated all day long
- 8 out of 10 users reported softer and silkier skin
- 3 out of 4 users reported smoother skin
- 1 out of 2 users reported skin looked younger after just 1 day

After 4 weeks:
- 3 out of 4 users reported the appearance of their skin was better after using the product
- 72% of women reported their skin looked younger
- 72% of women with skin conditions such as eczema, psoriasis, rosacea, or dermatitis reported the product helped ease their skin condition

Clean at Sephora
When you spot our Clean seal, you can be sure we’ve checked that this brand’s product is made without the ingredients you told us you’d most like to avoid.

Clean at Sephora™ is formulated without:
Sulfates SLS and SLES, parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, triclosan, triclocarban. All skincare, hair, and makeup brands with the Clean Seal have less than one percent of synthetic fragrances.
Size 0.5 oz/ 14 g · ITEM 1988815
exclusive· limited edition· buzzworthy· online only
$30.00

Love it...Holy Grail...I was shocked how good my concealer looked!...Taking into account the ingredients of the cream and the result I've seen I feel very good with it, I'm using it every night before I go to sleep, I know there are people who use it before applying makeup but I do not, so only the I use it at night and I see that my dark circles, although they were not very marked are becoming clearer and that area of the eyes looks more radiant.
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry
✔ Sensitive

What it is:
A moisturizing under-eye cream formulated with avocado oil to hydrate and smooth the delicate eye area.

Solutions for:
- Dryness

If you want to know more…
This luxurious eye cream gently moisturizes the eye area without migrating into the eyes. Perfect for use under eye makeup, it contains highly effective natural ingredients that provide essential daily hydration and protection. The eye area is left softer, suppler, and more youthful-looking.

What else you need to know:
This product is ophthalmologist and dermatologist tested.

Kiehl’s is inspired by its rich heritage as an old-world apothecary, applying over 165 years’ worth of cosmetic, pharmaceutical, herbal, and medicinal knowledge into the formulations. They utilize the finest natural ingredients and incorporate advanced scientific technologies to ensure the highest quality and most efficacious formulas without compromise. They are protective of the environment as they maximize the use of renewable, sustainable, and biodegradable ingredients. Kiehl’s proudly stands behind the quality, efficacy, and safety of each of their products.
ITEM 1953009
COLOR: Pink [ 2 more colors ]
exclusive· limited edition· buzzworthy· online only
$149.00

Not bad...Love it....Used for one day - pimple disappeared...I've noticed that if I catch a spot early-on, and immediately treat it 2-3 times consecutively with my Espada, the pimple heals either the next day or the whitehead comes up and clears within 2-3 days, which is a huge improvement from how long I usually wait out a pimple (a week or more).
What it is: A device that uses the dual power of laser-focused blue LED light and T-Sonic pulsations to address acne-causing bacteria, painlessly, in as little as 30 seconds.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Blemishes

What Else You Need to Know: The ultra-hygienic silicone surface inhibits bacterial growth. The blue LED light activates when the device touches the skin to address bacteria. T-Sonic pulsations support natural blood microcirculation to facilitate the skin’s renewal. Red, cross-shaped light precisely targets blemishes. ESPADA is FDA-approved.
Size 1.7 oz/ 50 mL · ITEM 2070944
exclusive· limited edition· buzzworthy· online only
$44.00

Love it...LOVE IT!...After a week, the pimples were almost all gone....I don't a lot of acne just the occasional pimple when I'm in my period but I felt it did a lot of cleaning in my face it felt like it had cleaned my pores and left my skin feeling soft.
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Sensitive

What it is:
A powerful treatment with five clinically proven acne-clearing acids to clear existing acne and help prevent future breakouts.

Solutions for:
- Acne
- Oiliness
- Pores

If you want to know more…
This medicated lightweight gel serum is clinically proven to reduce overall acne in just one week. Salicylic acid combines with lysophosphatidic, hydroxydecanoic, sebacic, and glycolic acids in penta-acid technology to clear skin of acne-causing bacteria, oiliness, and blackheads while minimizing dryness and irritation.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
Five acids. Clear skin. Proprietary penta-acid technology is salicylic acid combined with lysophosphatidic, hydroxydecanoic, sebacic, and glycolic acids to reduce pimples, blackheads, and whiteheads. This product is non-irritating, non-drying, and free of gluten, alcohol, and animal-derived ingredients.

"I have seen many patients develop a tolerance to prescription acne treatments, and when they stop working, it’s devastating. Treating acne demands a more holistic approach that includes lifestyle, nutrition, and advances in topical skincare. I developed Outsmart Acne™ Clarifying Treatment to be used as part of a whole-person regimen to help skin stay consistently clear."—Howard Murad, M.D., FAAD

Murad is cruelty-free, and is proud to deliver high-performance formulas that are tested on people, not animals.

Research results:
Clinically tested by an independent laboratory and proven safe for sensitive skin.

In clinical expert grading:
- 96% of subjects had reduced pimples, blackheads, and whiteheads in just 1 week
Size 1 oz/ 30 mL · ITEM 2126001
exclusive· limited edition· buzzworthy· online only
$95.00

lOVE it...Works ok...Great for acne prone skin....that is such s a great treatment for the skin.As I get older my skin was getting fine lines,wrinkles.After I received this product I was using it twice a day in the morning and in the evening.Maybe after one week and a half I started feeling how was changing my skin it became more softer,started to look more healthier and fine lines wasn't visible so much any more,i was feeling not only from outside but also from inside.I will keep continue using this product as I love the results and my skin lo
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry

What it is:
A fast-absorbing treatment infused with professional-strength 1.25 percent retinol and a blend of antioxidants and anti-irritants.

Solutions for:
- Fine lines and wrinkles
- Dullness and uneven texture
- Loss of firmness and elasticity

If you want to know more…
This supercharged nighttime serum combines 1.25 percent Retinol with Bakuchiol, a plant-derived retinol-mimicking compound to deliver younger-looking skin. Lancer’s proprietary CoRetinol Technology dramatically softens the look of wrinkles and expression lines, improving the appearance of skin elasticity, texture, and tone. Collagen and prickly pear extracts round out this advanced treatment to infuse the skin with plumping hydration while minimizing the look of redness and dryness for a firmer, smoother appearance.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
Retinol is a type of retinoid famed for its anti-aging properties. Enzymes in the body convert the retinol into retinoic acid.