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Sephora customers often prefer the following products when searching for Pimple Spot Treatments.

Browse the top-ranked list of Pimple Spot Treatments below along with associated reviews and opinions.

Size 0.5 oz/ 15 mL · ITEM 1933100
exclusive· limited edition· buzzworthy· online only
$22.00

THE BEST...LOVE LOVE LOVE...Blemish gone the next morning!...I will have to say though this dried the spots up significantly and became a little flakey - but I didn't mind because I know it was killing those pimples and I just felt like new skin was formulating in those areas!!!
Which skin type is it good for?
✔ Oily
✔ Combination

What it is:
A maximum strength two percent salicylic acid gel formula that reduces blemish size and redness in as little as four hours.

Solutions for:
- Acne and blemishes
- Oiliness
- Pores

If you want to know more…
This maximum strength formula contains salicylic acid to exfoliate, clear pores, and smooth skin. Inspired by pine and thyme extracts, a patented complex fights irritants while preserving skin’s healthy balance. The clear gel formula works well under makeup without pilling or peeling to treat blemishes while concealing.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
The cooling gel soothes skin on contact while going to work immediately to treat blemishes. Apply Rapid Relief Acne Spot Treatment when a blemish is emerging for ultimate control over acne.

This product is an Allure Best of Beauty award winner.

Research results:
In a Murad sponsored study:
- 97% agree blemish appearance improved after just 1 day
Size 0.33 oz/10 mL · ITEM 2021046
exclusive· limited edition· buzzworthy· online only
$16.00

Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry
✔ Sensitive

What it is:
An acne treatment gel with a proprietary skin-recovery complex to clear breakouts quickly and promote balanced, smooth skin with no redness, dark spots, or scarring.

Solutions for:
- Acne and blemishes
- Pores
- Redness

If you want to know more…
This formula gently and effectively treats visible acne overnight using a skin-recovery complex that blends salicylic acid, vitamin B3, azelaic acid, caffeine, and other complexion clearers. The formula helps fight redness and unclog pores while calming and soothing post-breakout skin. The result is a clarified, glowing complexion free of redness, dark spots, and hyperpigmentation.

What else you need to know:
This product is dermatologist tested, hypoallergenic, vegan, and fragrance-free.

Clean at Sephora
When you spot our Clean seal, you can be sure we’ve checked that this brand’s product is made without the ingredients you told us you’d most like to avoid.

Clean at Sephora™ is formulated without:
Sulfates SLS and SLES, parabens, formaldehydes, formaldehyde-releasing agents, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, triclosan, triclocarban. All skincare, hair, and makeup brands with the Clean Seal have less than one percent of synthetic fragrances.
Size 0.5 oz/ 15 ml · ITEM 1989276
exclusive· limited edition· buzzworthy· online only
$18.00

Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination

What it is:
A spot treatment that targets problem areas on contact to help clear blemishes.

Solutions for:
- Oiliness
- Acne and blemishes

If you want to know more…
Formulated for acne prone or oily skin, this treatment contains two percent salicylic acid to penetrates into pores and reduce acne breakouts. salicylic acid has antibacterial properties to suppress acne-causing bacteria and diminish breakouts. Frankincense helps to reduce oiliness, and ginger root extract soothes and absorbs excess oil for visibly calmer skin.

What else you need to know:
This product is tested under dermatologist supervision. It was inspired by the original Blue Astringent Herbal Lotion, which was formulated in 1964.

Kiehl’s is inspired by its rich heritage as an old-world apothecary, applying over 165 years’ worth of cosmetic, pharmaceutical, herbal, and medicinal knowledge into the formulations. They utilize the finest natural ingredients and incorporate advanced scientific technologies to ensure the highest quality and most efficacious formulas without compromise. They are protective of the environment as they maximize the use of renewable, sustainable, and biodegradable ingredients. Kiehl’s proudly stands behind the quality, efficacy, and safety of each of their products.
Size 0.68 oz/ 20 mL · ITEM 1989318
exclusive· limited edition· buzzworthy· online only
$28.00

Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination

What it is:
A spot treatment that targets problem areas on contact to help clear blemishes.

Solutions for:
- Oiliness
- Acne and blemishes

If you want to know more…
Breakout Control Targeted Acne Spot Treatment effectively targets acne and blemishes at the source. Salicylic acid refines skin texture and possesses anti-bacterial properties to suppress acne-causing bacteria, oil-absorbing ginger root extract delivers gingerols to soothe skin, and frankincense helps reduce sebum production.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
This product was inspired by the original Blue Astringent Herbal Lotion formulated in 1964, and is tested under dermatologist supervision. As part of your acne-free skincare routine, start using the Blue Herbal Gel Cleanser, followed by the Blue Astringent Herbal Lotion and Blue Herbal Moisturizer.

Kiehl’s is inspired by its rich heritage as an old-world apothecary, applying over 165 years’ worth of cosmetic, pharmaceutical, herbal, and medicinal knowledge into the formulations. They utilize the finest natural ingredients and incorporate advanced scientific technologies to ensure the highest quality and most efficacious formulas without compromise. They are protective of the environment as they maximize the use of renewable, sustainable, and biodegradable ingredients. Kiehl’s proudly stands behind the quality, efficacy, and safety of each of their products.
Size 2.3 oz · ITEM 1817972
exclusive· limited edition· buzzworthy· online only
$48.00

What it is:
A 10 percent aromatic sulfur mask that dries quickly and clears up acne blemishes.

What it is formulated to do:
This deep pore penetrating, therapeutic formulation absorbs excess surface skin oils, exfoliates dead skin cells, and leaves complexion feeling healthy and refreshed. It clarifies and helps prevent the development of new blemishes and blackheads while allowing skin to heal. Witch hazel and kaolin help purify, and botanicals help calm and soothe acne-prone skin.

What it is formulated WITHOUT:
- Parabens

What else you need to know:
This product is dermatologist tested and approved, allergy tested, hypoallergenic, non-irritating, noncomedogenic, and cruelty-free. It does not contain dye.
Size 1 oz/ 30 mL · ITEM 1592831
exclusive· limited edition· buzzworthy· online only
$27.00

Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry

What it is:
A daily treatment gel for acne-clearing results equal to a leading topical prescription.

Solutions for:
- Acne and blemishes
- Pores
- Oiliness

If you want to know more…
This ultra-powerful daily treatment gel is powered by Clinique’s four-in-one clearing complex with salicylic acid to start clearing blemishes instantly and help prevent new ones from forming. You can make visibly clearer skin a way of life.

What it is formulated WITHOUT:
- Parabens

What else you need to know:
This product is allergy tested, non-acnegenic, and free of oil and fragrance.

This product is an Allure Best of Beauty award winner.
Size 0.5 oz/ 15 mL · ITEM 1592856
exclusive· limited edition· buzzworthy· online only
$18.00

Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry

What it is:
A daily treatment gel for acne-clearing results equal to a leading topical prescription.

Solutions for:
- Acne and blemishes
- Pores
- Oiliness

If you want to know more…
This ultra-powerful daily treatment gel is powered by Clinique’s four-in-one clearing complex with salicylic acid to start clearing blemishes instantly and help prevent new ones from forming. You can make visibly clearer skin a way of life.

What it is formulated WITHOUT:
- Parabens

What else you need to know:
This product is allergy tested, non-acnegenic, and free of oil and fragrance.

This product is an Allure Best of Beauty award winner.
Size 0.5 oz · ITEM 1843770
exclusive· limited edition· buzzworthy· online only
$19.00

Love it....Works great!...pimples were gone in 3 days....Normally all acne clearing things with salicylic acid in them dry my skin out so bad but I had this months long break out that I decide to try this on and it cleared up in a little over a week.
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination

What it is:
An extra strength, non-drying, non-irritating, oil-controlling, invisible acne treatment.

Solutions for:
- Acne and blemishes
- Oiliness

If you want to know more…
This powerful, oil-controlling acne treatment contains five percent colloidal sulfur, a four percent glycolic acid complex, aloe vera, allantoin, botanical extracts, and vitamins C, E, and pro vitamin B5. Colloidal sulfur absorbs excess oil and controls existing breakouts and the formation of future acne, while glycolic acid helps to exfoliate dead surface skin cells and support natural cellular turnover. Aloe vera soothes and hydrates the skin for a comfortable complexion.

What it is formulated WITHOUT:
- Parabens
Size 1 oz · ITEM 1167147
exclusive· limited edition· buzzworthy· online only
$26.00

Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry

What it is:
An effective blemish-fighting acne treatment to minimize pimples, zits, and help prevent future breakouts.

Solutions for:
- Acne/blemishes
- Pores

If you want to know more…
Kate's bestselling EradiKate™ Acne Treatment is specifically formulated with the highest level of sulfur allowed to effectively fight blemishes, reduce acne, and help keep skin free of new breakouts. BHAs are designed to reduce the appearance of enlarged pores while zinc oxide, a natural mineral, provides oil control by absorbing excess sebum. The result is clearer skin that lasts.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
EradiKate Acne Treatment is most effective when applied to affected areas as soon as blemishes or pimples are noticed.

"Do you have a pimple you can feel but can't see? Use EradiKate on the area immediately to help prevent it from surfacing."—Kate Somerville, Founder

Kate Somerville has been certified cruelty-free by PETA, solidifying the brand’s commitment to never test their products or ingredients on animals.
Size 8 oz/ 227 g · ITEM 1376276
exclusive· limited edition· buzzworthy· online only
$43.00

I love is mask....Sexy strong hair...It's smells good though....i got a free sample when I ordered online so I tried it and love it it brings my dry damaged hair back to life and does not weight it down I love living proof they scored another hit cause I am already addicted to there straight making no frizz line
What it is: A deep conditioning mask treatment that repairs dry, damaged hair by nourishing strands, leaving hair visibly healthier, 20 times stronger, and shinier.

Hair Type: Straight, Wavy, Curly, and Coily

Hair Texture: Fine, Medium, and Thick

Hair Concerns: Dryness, Shine, and Damage/Split Ends/Breakage

Formulation: Mask

Fragrance: Fresh Citrus and Fruits

Highlighted Ingredients:
- Patented Healthy Hair Molecule (OFPMA): Restores damaged cuticles and moisture levels, strengthens hair, and protects it from future damage.

Ingredient Callouts: Free of parabens and silicone. This product is also cruelty-free.

What Else You Need to Know: A tacuma butter delivers long-term conditioning, glycolic acid smooths and softens hair, and Living Proof’s patented healthy hair molecule (OFPMA) restores damaged cuticles and moisture levels, strengthens hair, and protects from future damage. The result: hair looks and feels visibly healthier and 20 times stronger.
Size 1 oz/ 30 mL · ITEM 1418581
exclusive· limited edition· buzzworthy· online only
$105.00

Love it...No joke....My skin is visibly smoother and no breakouts....Since I first started Good Genes I am now also using Ceramic Slip Cleanser, Luna oil at night along with Saturn as a spot treatment and Good Genes in the morning, my skin is almost totally clear which is absolutely amazing in addition to noticeably brighter, firmer skin!
What it is: An all-in-one AHA treatment, powered by lactic acid, that clarifies, smooths, and retexturizes the appearance of skin.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Fine lines and wrinkles, Pores, Dark spots

Formulation: Serum

Highlighted Ingredients:
- Purified Lactic Acid: Hydrates and exfoliates the surface layers of the skin, revealing a more clarified, fresher, smoother, younger-looking complexion.
- Licorice and Lemongrass: Brighten the appearance of dark spots and discolorations.
- Prickly Pear Extract: Soothes the appearance of surface redness, while supporting a calmer, more even-toned complexion.

Ingredient Callouts: Free of sulfates SLS and SLES, parabens, phthalates, mineral oil, retinyl palmitate, oxybenzone, coal tar, hydroquinone, triclosan, and triclocarban, and contains less than one percent of synthetic fragrances. This product is also vegan, cruelty-free, gluten-free, and comes in recyclable packaging.

What Else You Need to Know: Good Genes is clinically proven to plump the look of fine lines and wrinkles in as few as three minutes. Formulated with high potency, purified grade lactic acid, it exfoliates the dull surface of the skin for clarity, radiance, and younger-looking skin. The formula is enhanced with licorice extract to visibly brighten the appearance of age spots and discolorations.

Clinical Results: Results obtained via profilometry analysis:
- 100% of women said their skin looked and felt significantly smoother and more radiant, with visibly reduced lines and wrinkles after application
- 100% of women said this was the most effective skin-plumping product they have ever used and would definitely recommend this product to a friend
Size 2 x 2 oz tubes/ 60 mL · ITEM 1765528
exclusive· limited edition· buzzworthy· online only
$42.00

Expensive but effective....Smells great and works wonders....I absolutely fell in love with the sample that I received.
What it is: An innovative and lightweight hair therapy that is for damaged hair.

Hair Type: Straight, Wavy, Curly, and Coily

Hair Texture: Fine, Medium, and Thick

Hair Concerns: Dryness, Shine, and Frizz

Formulation: Cream

Highlighted Ingredients:
- Jojoba Oil, Mirabelle Plum, Olive Oil, and Moringa Seed Oil: Provide deep hydration and shine. 
- Rice Protein: Protects hair fibers from the oxidative damage generated and strengthens strands. 
- Specialty Linseed Extract: Helps to conserve melanin in the hair follicle.

Ingredient Callouts: Free of sulfates SLS & SLES and parabens.

What Else You Need to Know: This two-step treatment instantly repairs hair—leaving it soft, manageable, and frizz-free up to 24 hours. Step 1 treats hair cuticles for optimal penetration of conditioners and four oils. Step 2 seals and locks in nutrition for lasting hydration, while rice proteins strengthen and protect color.
Size 1 oz/ 30 mL · ITEM 1572445
exclusive· limited edition· buzzworthy· online only
$56.00

love it...Love It!...I purchased this product for my little sister after years of her fighting horrible acne (I was the lucky one and never had a blemish), she was so distraught and scared of anything moisturizing that when this came out I immediately bought it for her since I am a huge fan of this entire line....I purchased this product for my little sister after years of her fighting horrible acne (I was the lucky one and never had a blemish), she was so distraught and scared of anything moisturizing that when this came out I immediately bought it for her since I am a huge fan of this entire line.
Which skin type is it good for?
✔ Combination
✔ Dry
✔ Sensitive

What it is:
A 100 percent natural, emulsifier-free treatment serum that visibly plumps and deeply hydrates.

Solutions for:
- Fine lines and wrinkles
- Loss of firmness and elasticity

If you want to know more…
Josie’s revolutionary anti-aging Pure Argan Milk marries the hydration of skin-balancing purified water with rejuvenating 100% Pure Argan Oil for plumper-looking, nourished skin. This lightweight yet super-intensive hydrating serum penetrates deeply and absorbs quickly to preserve the elasticity and bounce of skin's youthful cushion. The 100% Pure Argan Oil repairs and fortifies with a weightless combination of essential fatty acids, antioxidants, and vitamin E to reveal fresher, healthier, more radiant skin packed with long-lasting moisture. Use under Face Butter and Argan Oil for amplified moisture and glow.

What else you need to know:
This product is vegan, cruelty-free, and formulated without gluten, GMO, synthetic fragrance, and formaldehyde.

Research results:
Allure Beauty Enthusiasts Panel, October 2013 in a 4-week product trial; each participant received a complimentary full-size Pure Argan Milk and used it twice daily; 222 respondents to the 24-hour survey; 196 respondents:
- 85% of women reported their skin was more hydrated and felt hydrated all day long
- 8 out of 10 users reported softer and silkier skin
- 3 out of 4 users reported smoother skin
- 1 out of 2 users reported skin looked younger after just 1 day

After 4 weeks:
- 3 out of 4 users reported the appearance of their skin was better after using the product
- 72% of women reported their skin looked younger
- 72% of women with skin conditions such as eczema, psoriasis, rosacea, or dermatitis reported the product helped ease their skin condition

Clean at Sephora
Clean at Sephora is formulated without a list of over 50 ingredients, including sulfates (SLS and SLES), parabens, phthalates, and more. For the full list, check out the Ingredients tab.
Size 5 oz/ 150 ml · ITEM 1989292
exclusive· limited edition· buzzworthy· online only
$22.00

I love it!...ehhh it's ok...Less breakouts...I have only been using it for a little over 3 weeks but it really works.
Which skin type is it good for?
✔ Oily
✔ Combination

What it is:
A high foaming acne cleanser that helps purify pores, removing traces of dirt and oil.

Solutions for:
- Oiliness
- Acne and blemishes

If you want to know more…
Inspired by the iconic Blue Astringent Herbal Lotion formulated in 1964, this oil-fighting cleanser is formulated to help clear blemishes, pimples, blackheads, and whiteheads, and prevent new ones from forming. It contains salicylic acid to penetrate deep into pores.

What else you need to know:
This product is tested under dermatologist supervision.

Kiehl’s is inspired by its rich heritage as an old-world apothecary, applying over 165 years’ worth of cosmetic, pharmaceutical, herbal, and medicinal knowledge into the formulations. They utilize the finest natural ingredients and incorporate advanced scientific technologies to ensure the highest quality and most efficacious formulas without compromise. They are protective of the environment as they maximize the use of renewable, sustainable, and biodegradable ingredients. Kiehl’s proudly stands behind the quality, efficacy, and safety of each of their products.
Size 1 oz/ 30 mL · ITEM 2126001
exclusive· limited edition· buzzworthy· online only
$95.00

Loved it...The Best!...Great product, doesn't cause breakouts...I've been using Lancer for a couple of weeks and can really tell a difference, my skin use to be dull and had quite a few fine lines and wrinkles but after using this product it really seems to be helping a lot I can tell that my skin is now smoother a d a lot softer.
Which skin type is it good for?
✔ Normal
✔ Oily
✔ Combination
✔ Dry

What it is:
A fast-absorbing treatment infused with professional-strength 1.25 percent retinol and a blend of antioxidants and anti-irritants.

Solutions for:
- Fine lines and wrinkles
- Dullness and uneven texture
- Loss of firmness and elasticity

If you want to know more…
This supercharged nighttime serum combines 1.25 percent Retinol with Bakuchiol, a plant-derived retinol-mimicking compound to deliver younger-looking skin. Lancer’s proprietary CoRetinol Technology dramatically softens the look of wrinkles and expression lines, improving the appearance of skin elasticity, texture, and tone. Collagen and prickly pear extracts round out this advanced treatment to infuse the skin with plumping hydration while minimizing the look of redness and dryness for a firmer, smoother appearance.

What it is formulated WITHOUT:
- Parabens
- Sulfates
- Phthalates

What else you need to know:
Retinol is a type of retinoid famed for its anti-aging properties. Enzymes in the body convert the retinol into retinoic acid.
ITEM 2171049
exclusive· limited edition· buzzworthy· online only
$35.00

I have combination mature skin....Effective acne system for mature combo skin...I received this 3 step treatment as a gift, and was super excited to dive in with all the hype.
What it is: An original Combination Therapy® three-step regimen developed to clear existing acne breakouts and help prevent future ones from occurring.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Acne and Blemishes and Oiliness

Formulation: Cream/Liquid/Lotion

Highlighted Ingredients:
- Benzoyl Peroxide 2.5%: A prescription-strength BPO with micronized particles designed to penetrate deep into pores to kill acne causing bacteria at its source.
- Hyaluronic Acid: Designed to help maintain skin hydration due to its ability to act as a moisture magnet and attract water to the skin; helps enhance the skin’s softness and suppleness.
- Glycolic Acid: An alpha hydroxy acid designed to exfoliate the skin.
- Allantoin: In the herb comfrey, this extract helps moisturize and promotes the look of healthy-looking skin.

What Else You Need to Know: With micro-crystal benzoyl peroxide, Proactiv targets the root causes of acne—bacteria, oil production, and dead skin cell buildup—to soothe redness and acne-prone skin. The Renewing Cleanser and Repairing Treatment contains benzoyl peroxide, a proven acne medicine known to kill and prevent acne bacteria. The alcohol-free Revitalizing Toner helps to gently remove excess oil and soften acne-prone skin with glycolic acid.

This Set Contains:
- 2 oz/ 59.14 mL Renewing Cleanser
- 2 oz/ 59.14 mL Revitalizing Toner
- 1 oz/ 29.5 mL Repairing Treatment
ITEM 2171056
exclusive· limited edition· buzzworthy· online only
$80.00

Helped Me With My Acne...And, it feels gentle on your skin.
What it is: An original Combination Therapy® three-step regimen developed to clear existing acne breakouts and help prevent future ones from occurring.

Skin Type: Normal, Dry, Combination, and Oily

Skincare Concerns: Acne and Blemishes and Oiliness

Formulation: Cream/Liquid/Lotion

Highlighted Ingredients:
- Benzoyl Peroxide 2.5%: A prescription-strength BPO with micronized particles designed to penetrate deep into pores to kill acne causing bacteria at its source.
- Hyaluronic Acid: Designed to help maintain skin hydration due to its ability to act as a moisture magnet and attract water to the skin; helps enhance the skin’s softness and suppleness.
- Glycolic Acid: An alpha hydroxy acid designed to exfoliate the skin.
- Allantoin: In the herb comfrey, this extract helps moisturize and promotes the look of healthy-looking skin.

What Else You Need to Know: With micro-crystal benzoyl peroxide, Proactiv targets the root causes of acne—bacteria, oil production, and dead skin cell buildup—to soothe redness and acne-prone skin. The Renewing Cleanser and Repairing Treatment contains benzoyl peroxide, a proven acne medicine known to kill and prevent acne bacteria. The alcohol-free Revitalizing Toner helps to gently remove excess oil and soften acne-prone skin with glycolic acid.

This Set Contains:
- 6 oz/ 177.4 mL Renewing Cleanser
- 6 oz/ 177.4 mL Revitalizing Toner
- 3 oz/ 88.7 mL Repairing Treatment
Size 0.15 oz/ 4.3 g · ITEM 1378215
COLOR: Translucent [ 1 more colors ]
exclusive· limited edition· buzzworthy· online only
$26.00

love it!...Love this...I must say I was pretty hesitant to spend $25 on a lip treatment, but since I received a gift card for Sephora for a Christmas gift I figured what the heck, not really my money anyways!...I don't live in a cold climate, so I can't speak for those who have chapped lips year-round, but I put this on at night and my lips feel smooth all day.
What it is: A bestselling lip balm that hydrates for 24 hours and smooths the look of wrinkles for visibly fuller lips.

Skincare Concerns: Dryness, Fine Lines and Wrinkles, and Loss of Firmness and Elasticity

Formulation: Balm

Highlighted Ingredients:
- Sugar: Prevents moisture loss.
- Sea Fennel: Helps to smooth fine lines and wrinkles and define the lip area.
- Orange Extract: Protects the lips.

Ingredient Callouts: Free of sulfates SLS and SLES, parabens, and phthalates.

What Else You Need to Know: The age-defying lip treatment is proven to improve volume and definition (read: plumper pout), making it ideal for overnight or a base layer for lipstick. The sugar formula also contains sea fennel to help smooth fine lines, antioxidant-rich orange extract, and moisturizing hyaluronic acid spheres.

Clinical Results: In-vivo test:
- 100% noticed their lips were more moisturized, nourished, and supple
- 100% reported healthier-looking, softer, silkier lips
- 100% felt it protected their lips overnight, removed dry flakes, and improved dry lips
- 97% reported improved elasticity and smoothness around the lip area
- 93% felt it retexturized and visibly improved the overall appearance of their lips