PDRN stands for polydeoxyribonucleotide, a term for short chains of DNA. It is an ingredient found in skincare formulas such as serums, essences, and creams.
PDRN appears in several skincare categories, including toners, essences, ampoules, serums, moisturizers, and facial masks. The product category determines its format and application method.
PDRN used in skincare is commonly derived from salmon or trout DNA. Ingredient origins can vary by formula, so the brand’s ingredient information is the best place to confirm the source.
Placement depends on the product type. A PDRN toner or essence generally follows cleansing, a serum goes before moisturizer, and a cream belongs at the moisturizing step. Follow the application directions on the product label.
PDRN skincare can have watery, gel-like, milky, or creamy textures. Toners and essences are often fluid, serums range from liquids to gels, and creams tend to have a richer consistency.
